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PolyI:C Upregulated CCR5 and Promoted THP-1-Derived Macrophage Chemotaxis via TLR3/JMJD1A Signalling

OBJECTIVE: This study aimed to evaluate the specific roles of polyinosinic:polycytidylic acid (polyI:C) in macrophage chemotaxis and reveal the potential regulatory mechanisms related to chemokine receptor 5 (CCR5). MATERIALS AND METHODS: In this experimental study, THP-1-derived macrophages (THP1-M...

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Detalles Bibliográficos
Autores principales:	Yu, Xiaoxiao, Wang, Huayang, Shao, Hongjia, Zhang, Cuijuan, Ju, Xiuli, Yang, Jie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Royan Institute 2020
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6947015/ https://www.ncbi.nlm.nih.gov/pubmed/31863658 http://dx.doi.org/10.22074/cellj.2020.6713

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