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Synaptic Pruning by Microglia in Epilepsy

Structural and functional collapse of the balance between excitatory (E) and inhibitory (I) synapses, i.e., synaptic E/I balance, underlies the pathogeneses of various central nervous system (CNS) disorders. In epilepsy, the synaptic E/I balance tips toward excitation; thus, most of the existing epi...

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Detalles Bibliográficos
Autores principales: Andoh, Megumi, Ikegaya, Yuji, Koyama, Ryuta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6947403/
https://www.ncbi.nlm.nih.gov/pubmed/31818018
http://dx.doi.org/10.3390/jcm8122170