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Anti-ApoA-1 IgGs in Familial Hypercholesterolemia Display Paradoxical Associations with Lipid Profile and Promote Foam Cell Formation

Aims: Anti-Apolipoprotein A-1 autoantibodies (anti-ApoA-1 IgG) promote atherogenesis via innate immune receptors, and may impair cellular cholesterol homeostasis (CH). We explored the presence of anti-ApoA-1 IgG in children (5–15 years old) with or without familial hypercholesterolemia (FH), analyzi...

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Detalles Bibliográficos
Autores principales: Pagano, Sabrina, Magenta, Alessandra, D’Agostino, Marco, Martino, Francesco, Barillà, Francesco, Satta, Nathalie, Frias, Miguel A., Ronca, Annalisa, Mach, François, Gencer, Baris, Favari, Elda, Vuilleumier, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6947407/
https://www.ncbi.nlm.nih.gov/pubmed/31766415
http://dx.doi.org/10.3390/jcm8122035