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A Nomogram to Predict the Outcome of Fine Needle Aspiration Cytology in Head and Neck Masses

Fine needle aspiration cytology (FNAC) is an important diagnostic tool for tumors of the head and neck. However, non-diagnostic or inconclusive results may occur and lead to delay in treatment. The aim of this study was to evaluate the factors that predict a successful FNAC. A retrospective search w...

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Autores principales: Kotowski, Ulana, Brkic, Faris F., Koperek, Oskar, Pablik, Eleonore, Grasl, Stefan, Grasl, Matthaeus Ch., Erovic, Boban M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6947452/
https://www.ncbi.nlm.nih.gov/pubmed/31766590
http://dx.doi.org/10.3390/jcm8122050
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author Kotowski, Ulana
Brkic, Faris F.
Koperek, Oskar
Pablik, Eleonore
Grasl, Stefan
Grasl, Matthaeus Ch.
Erovic, Boban M.
author_facet Kotowski, Ulana
Brkic, Faris F.
Koperek, Oskar
Pablik, Eleonore
Grasl, Stefan
Grasl, Matthaeus Ch.
Erovic, Boban M.
author_sort Kotowski, Ulana
collection PubMed
description Fine needle aspiration cytology (FNAC) is an important diagnostic tool for tumors of the head and neck. However, non-diagnostic or inconclusive results may occur and lead to delay in treatment. The aim of this study was to evaluate the factors that predict a successful FNAC. A retrospective search was performed to identify all patients who received an FNAC at the Department of Otorhinolaryngology, Head and Neck Surgery, Medical University of Vienna. The variables were patients’ age and sex, localization and size of the punctured structure, previous radiotherapy, experience of the head and neck surgeon, experience of the pathologist and the FNAC result. Based on these parameters, a nomogram was subsequently created to predict the probability of accurate diagnosis. After performing 1221 FNACs, the size of the punctured lesion (p = 0.0010), the experience of the surgeon and the pathologist (p = 0.00003) were important factors for a successfully procedure and reliable result. FNACs performed in nodes smaller than 20 mm had a significantly worse diagnostic outcome compared to larger nodes (p = 0.0004). In conclusion, the key factors for a successful FNAC are nodal size and the experience of the head and neck surgeon and the pathologist.
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spelling pubmed-69474522020-01-13 A Nomogram to Predict the Outcome of Fine Needle Aspiration Cytology in Head and Neck Masses Kotowski, Ulana Brkic, Faris F. Koperek, Oskar Pablik, Eleonore Grasl, Stefan Grasl, Matthaeus Ch. Erovic, Boban M. J Clin Med Article Fine needle aspiration cytology (FNAC) is an important diagnostic tool for tumors of the head and neck. However, non-diagnostic or inconclusive results may occur and lead to delay in treatment. The aim of this study was to evaluate the factors that predict a successful FNAC. A retrospective search was performed to identify all patients who received an FNAC at the Department of Otorhinolaryngology, Head and Neck Surgery, Medical University of Vienna. The variables were patients’ age and sex, localization and size of the punctured structure, previous radiotherapy, experience of the head and neck surgeon, experience of the pathologist and the FNAC result. Based on these parameters, a nomogram was subsequently created to predict the probability of accurate diagnosis. After performing 1221 FNACs, the size of the punctured lesion (p = 0.0010), the experience of the surgeon and the pathologist (p = 0.00003) were important factors for a successfully procedure and reliable result. FNACs performed in nodes smaller than 20 mm had a significantly worse diagnostic outcome compared to larger nodes (p = 0.0004). In conclusion, the key factors for a successful FNAC are nodal size and the experience of the head and neck surgeon and the pathologist. MDPI 2019-11-22 /pmc/articles/PMC6947452/ /pubmed/31766590 http://dx.doi.org/10.3390/jcm8122050 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Kotowski, Ulana
Brkic, Faris F.
Koperek, Oskar
Pablik, Eleonore
Grasl, Stefan
Grasl, Matthaeus Ch.
Erovic, Boban M.
A Nomogram to Predict the Outcome of Fine Needle Aspiration Cytology in Head and Neck Masses
title A Nomogram to Predict the Outcome of Fine Needle Aspiration Cytology in Head and Neck Masses
title_full A Nomogram to Predict the Outcome of Fine Needle Aspiration Cytology in Head and Neck Masses
title_fullStr A Nomogram to Predict the Outcome of Fine Needle Aspiration Cytology in Head and Neck Masses
title_full_unstemmed A Nomogram to Predict the Outcome of Fine Needle Aspiration Cytology in Head and Neck Masses
title_short A Nomogram to Predict the Outcome of Fine Needle Aspiration Cytology in Head and Neck Masses
title_sort nomogram to predict the outcome of fine needle aspiration cytology in head and neck masses
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6947452/
https://www.ncbi.nlm.nih.gov/pubmed/31766590
http://dx.doi.org/10.3390/jcm8122050
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