Gene‐Hydrogel Microenvironments: Gene‐Hydrogel Microenvironment Regulates Extracellular Matrix Metabolism Balance in Nucleus Pulposus (Adv. Sci. 1/2020)

In degenerative diseases, microenvironment deterioration is often followed by a vicious circle of cell death and aggravation of microenvironment deterioration. To break the cycle, a gene‐hydrogel microenvironment is constructed in article number https://doi.org/10.1002/advs.201902099 by Yuhui Zhang,...

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Autores principales: Chen, Wei, Chen, Hao, Zheng, Dandan, Zhang, Hongbo, Deng, Lianfu, Cui, Wenguo, Zhang, Yuhui, Santos, Hélder A., Shen, Hongxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Cover Picture
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6947492/
http://dx.doi.org/10.1002/advs.202070001
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author Chen, Wei
Chen, Hao
Zheng, Dandan
Zhang, Hongbo
Deng, Lianfu
Cui, Wenguo
Zhang, Yuhui
Santos, Hélder A.
Shen, Hongxing
author_facet Chen, Wei
Chen, Hao
Zheng, Dandan
Zhang, Hongbo
Deng, Lianfu
Cui, Wenguo
Zhang, Yuhui
Santos, Hélder A.
Shen, Hongxing
author_sort Chen, Wei
collection PubMed
description In degenerative diseases, microenvironment deterioration is often followed by a vicious circle of cell death and aggravation of microenvironment deterioration. To break the cycle, a gene‐hydrogel microenvironment is constructed in article number https://doi.org/10.1002/advs.201902099 by Yuhui Zhang, Hélder A. Santos, Hongxing Shen, and co‐workers in situ, which regulates the synthesis/catabolism balance of extracellular matrix in the nucleus pulposus of the intervertebral disc and improves the tissue microenvironment regeneration. [Image: see text]
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spelling pubmed-69474922020-01-09 Gene‐Hydrogel Microenvironments: Gene‐Hydrogel Microenvironment Regulates Extracellular Matrix Metabolism Balance in Nucleus Pulposus (Adv. Sci. 1/2020) Chen, Wei Chen, Hao Zheng, Dandan Zhang, Hongbo Deng, Lianfu Cui, Wenguo Zhang, Yuhui Santos, Hélder A. Shen, Hongxing Adv Sci (Weinh) Cover Picture In degenerative diseases, microenvironment deterioration is often followed by a vicious circle of cell death and aggravation of microenvironment deterioration. To break the cycle, a gene‐hydrogel microenvironment is constructed in article number https://doi.org/10.1002/advs.201902099 by Yuhui Zhang, Hélder A. Santos, Hongxing Shen, and co‐workers in situ, which regulates the synthesis/catabolism balance of extracellular matrix in the nucleus pulposus of the intervertebral disc and improves the tissue microenvironment regeneration. [Image: see text] John Wiley and Sons Inc. 2020-01-08 /pmc/articles/PMC6947492/ http://dx.doi.org/10.1002/advs.202070001 Text en © 2020 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Cover Picture
Chen, Wei
Chen, Hao
Zheng, Dandan
Zhang, Hongbo
Deng, Lianfu
Cui, Wenguo
Zhang, Yuhui
Santos, Hélder A.
Shen, Hongxing
Gene‐Hydrogel Microenvironments: Gene‐Hydrogel Microenvironment Regulates Extracellular Matrix Metabolism Balance in Nucleus Pulposus (Adv. Sci. 1/2020)
title Gene‐Hydrogel Microenvironments: Gene‐Hydrogel Microenvironment Regulates Extracellular Matrix Metabolism Balance in Nucleus Pulposus (Adv. Sci. 1/2020)
title_full Gene‐Hydrogel Microenvironments: Gene‐Hydrogel Microenvironment Regulates Extracellular Matrix Metabolism Balance in Nucleus Pulposus (Adv. Sci. 1/2020)
title_fullStr Gene‐Hydrogel Microenvironments: Gene‐Hydrogel Microenvironment Regulates Extracellular Matrix Metabolism Balance in Nucleus Pulposus (Adv. Sci. 1/2020)
title_full_unstemmed Gene‐Hydrogel Microenvironments: Gene‐Hydrogel Microenvironment Regulates Extracellular Matrix Metabolism Balance in Nucleus Pulposus (Adv. Sci. 1/2020)
title_short Gene‐Hydrogel Microenvironments: Gene‐Hydrogel Microenvironment Regulates Extracellular Matrix Metabolism Balance in Nucleus Pulposus (Adv. Sci. 1/2020)
title_sort gene‐hydrogel microenvironments: gene‐hydrogel microenvironment regulates extracellular matrix metabolism balance in nucleus pulposus (adv. sci. 1/2020)
topic Cover Picture
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6947492/
http://dx.doi.org/10.1002/advs.202070001
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