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Interleukin-1β Mediates Arterial Thrombus Formation via NET-Associated Tissue Factor

CANTOS reported reduced secondary atherothrombotic events in patients with residual inflammatory risk treated with the inhibitory anti-IL-1β antibody, Canakinumab. Yet, mechanisms that underlie this benefit remain elusive. Recent work has implicated formation of neutrophil extracellular traps (NETos...

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Detalles Bibliográficos
Autores principales: Liberale, Luca, Holy, Erik W., Akhmedov, Alexander, Bonetti, Nicole R., Nietlispach, Fabian, Matter, Christian M., Mach, François, Montecucco, Fabrizio, Beer, Jürg H., Paneni, Francesco, Ruschitzka, Frank, Libby, Peter, Lüscher, Thomas F., Camici, Giovanni G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6947515/
https://www.ncbi.nlm.nih.gov/pubmed/31779200
http://dx.doi.org/10.3390/jcm8122072

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