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LABAs and p38MAPK Inhibitors Reverse the Corticosteroid-Insensitivity of IL-8 in Airway Smooth Muscle Cells of COPD
Airway inflammation in chronic obstructive pulmonary disease (COPD) is partially insensitive/resistant to inhaled corticosteroids (ICS). ICS plus bronchodilator therapy has been discussed for COPD phenotypes with frequent exacerbations and participation of corticosteroid-sensitive type 2/eosinophili...
Autores principales: | Knobloch, Jürgen, Jungck, David, Kronsbein, Juliane, Stoelben, Erich, Ito, Kazuhiro, Koch, Andrea |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6947523/ https://www.ncbi.nlm.nih.gov/pubmed/31766770 http://dx.doi.org/10.3390/jcm8122058 |
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