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Changes to the TDP-43 and FUS Interactomes Induced by DNA Damage

[Image: see text] The RNA-binding proteins TDP-43 and FUS are tied as the third leading known genetic cause for amyotrophic lateral sclerosis (ALS), and TDP-43 proteopathies are found in nearly all ALS patients. Both the natural function and contribution to pathology for TDP-43 remain unclear. The i...

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Detalles Bibliográficos
Autores principales: Kawaguchi, Tetsuya, Rollins, Matthew G., Moinpour, Mahta, Morera, Andres A., Ebmeier, Christopher C., Old, William M., Schwartz, Jacob C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6947635/
https://www.ncbi.nlm.nih.gov/pubmed/31693373
http://dx.doi.org/10.1021/acs.jproteome.9b00575