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Fine-Needle Aspiration Cytology of Salivary Gland Lesions: A Revised Classification Based on “Milan System”—4years Experience of Tertiary Care Cancer Center of South India
BACKGROUND: Fine-needle aspiration cytology plays role in preoperative diagnosis of any salivary gland mass lesions. Because of heterogeneity of salivary gland lesions and cytomorphology overlap, a uniform 6-tier Milan classification proposed which could be helpful in better communication of reports...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6947727/ https://www.ncbi.nlm.nih.gov/pubmed/31942092 http://dx.doi.org/10.4103/JOC.JOC_68_18 |
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author | Mukundapai, Malathi Sharma, Neelam Patil, Akkamahadevi Gopal, Champaka |
author_facet | Mukundapai, Malathi Sharma, Neelam Patil, Akkamahadevi Gopal, Champaka |
author_sort | Mukundapai, Malathi |
collection | PubMed |
description | BACKGROUND: Fine-needle aspiration cytology plays role in preoperative diagnosis of any salivary gland mass lesions. Because of heterogeneity of salivary gland lesions and cytomorphology overlap, a uniform 6-tier Milan classification proposed which could be helpful in better communication of reports for patient's management. METHODS: Study included 4 years (2011–2015) retrospective data retrieval from cytology department of our Institute, which is a tertiary care cancer center of South India. Histopathology correlation was done wherever possible. RESULT: Total 253 cases were studied. Histopathological follow-up was available in 115 cases. Cases were categorized as nondiagnostic (1.58%), nonneoplastic (13.43%), benign (30%), atypia (0.8%), and suspicious for malignancy and malignant cytology (51.8%). The risk for malignancy was high for suspicious for malignancy and malignant cytological categories ranged from 96–100%. The sensitivity, specificity, and accuracy for diagnosing malignancy varied from 86.76%, 93.75%, and 89%, respectively. CONCLUSION: Risk stratification approach in classifying salivary gland cytology aspirate as per Milan system provides a standardized reporting and better communication to clinician. |
format | Online Article Text |
id | pubmed-6947727 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-69477272020-01-15 Fine-Needle Aspiration Cytology of Salivary Gland Lesions: A Revised Classification Based on “Milan System”—4years Experience of Tertiary Care Cancer Center of South India Mukundapai, Malathi Sharma, Neelam Patil, Akkamahadevi Gopal, Champaka J Cytol Original Article BACKGROUND: Fine-needle aspiration cytology plays role in preoperative diagnosis of any salivary gland mass lesions. Because of heterogeneity of salivary gland lesions and cytomorphology overlap, a uniform 6-tier Milan classification proposed which could be helpful in better communication of reports for patient's management. METHODS: Study included 4 years (2011–2015) retrospective data retrieval from cytology department of our Institute, which is a tertiary care cancer center of South India. Histopathology correlation was done wherever possible. RESULT: Total 253 cases were studied. Histopathological follow-up was available in 115 cases. Cases were categorized as nondiagnostic (1.58%), nonneoplastic (13.43%), benign (30%), atypia (0.8%), and suspicious for malignancy and malignant cytology (51.8%). The risk for malignancy was high for suspicious for malignancy and malignant cytological categories ranged from 96–100%. The sensitivity, specificity, and accuracy for diagnosing malignancy varied from 86.76%, 93.75%, and 89%, respectively. CONCLUSION: Risk stratification approach in classifying salivary gland cytology aspirate as per Milan system provides a standardized reporting and better communication to clinician. Wolters Kluwer - Medknow 2020 2019-12-23 /pmc/articles/PMC6947727/ /pubmed/31942092 http://dx.doi.org/10.4103/JOC.JOC_68_18 Text en Copyright: © 2019 Journal of Cytology http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Original Article Mukundapai, Malathi Sharma, Neelam Patil, Akkamahadevi Gopal, Champaka Fine-Needle Aspiration Cytology of Salivary Gland Lesions: A Revised Classification Based on “Milan System”—4years Experience of Tertiary Care Cancer Center of South India |
title | Fine-Needle Aspiration Cytology of Salivary Gland Lesions: A Revised Classification Based on “Milan System”—4years Experience of Tertiary Care Cancer Center of South India |
title_full | Fine-Needle Aspiration Cytology of Salivary Gland Lesions: A Revised Classification Based on “Milan System”—4years Experience of Tertiary Care Cancer Center of South India |
title_fullStr | Fine-Needle Aspiration Cytology of Salivary Gland Lesions: A Revised Classification Based on “Milan System”—4years Experience of Tertiary Care Cancer Center of South India |
title_full_unstemmed | Fine-Needle Aspiration Cytology of Salivary Gland Lesions: A Revised Classification Based on “Milan System”—4years Experience of Tertiary Care Cancer Center of South India |
title_short | Fine-Needle Aspiration Cytology of Salivary Gland Lesions: A Revised Classification Based on “Milan System”—4years Experience of Tertiary Care Cancer Center of South India |
title_sort | fine-needle aspiration cytology of salivary gland lesions: a revised classification based on “milan system”—4years experience of tertiary care cancer center of south india |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6947727/ https://www.ncbi.nlm.nih.gov/pubmed/31942092 http://dx.doi.org/10.4103/JOC.JOC_68_18 |
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