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Fine-Needle Aspiration Cytology of Salivary Gland Lesions: A Revised Classification Based on “Milan System”—4years Experience of Tertiary Care Cancer Center of South India

BACKGROUND: Fine-needle aspiration cytology plays role in preoperative diagnosis of any salivary gland mass lesions. Because of heterogeneity of salivary gland lesions and cytomorphology overlap, a uniform 6-tier Milan classification proposed which could be helpful in better communication of reports...

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Autores principales: Mukundapai, Malathi, Sharma, Neelam, Patil, Akkamahadevi, Gopal, Champaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6947727/
https://www.ncbi.nlm.nih.gov/pubmed/31942092
http://dx.doi.org/10.4103/JOC.JOC_68_18
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author Mukundapai, Malathi
Sharma, Neelam
Patil, Akkamahadevi
Gopal, Champaka
author_facet Mukundapai, Malathi
Sharma, Neelam
Patil, Akkamahadevi
Gopal, Champaka
author_sort Mukundapai, Malathi
collection PubMed
description BACKGROUND: Fine-needle aspiration cytology plays role in preoperative diagnosis of any salivary gland mass lesions. Because of heterogeneity of salivary gland lesions and cytomorphology overlap, a uniform 6-tier Milan classification proposed which could be helpful in better communication of reports for patient's management. METHODS: Study included 4 years (2011–2015) retrospective data retrieval from cytology department of our Institute, which is a tertiary care cancer center of South India. Histopathology correlation was done wherever possible. RESULT: Total 253 cases were studied. Histopathological follow-up was available in 115 cases. Cases were categorized as nondiagnostic (1.58%), nonneoplastic (13.43%), benign (30%), atypia (0.8%), and suspicious for malignancy and malignant cytology (51.8%). The risk for malignancy was high for suspicious for malignancy and malignant cytological categories ranged from 96–100%. The sensitivity, specificity, and accuracy for diagnosing malignancy varied from 86.76%, 93.75%, and 89%, respectively. CONCLUSION: Risk stratification approach in classifying salivary gland cytology aspirate as per Milan system provides a standardized reporting and better communication to clinician.
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spelling pubmed-69477272020-01-15 Fine-Needle Aspiration Cytology of Salivary Gland Lesions: A Revised Classification Based on “Milan System”—4years Experience of Tertiary Care Cancer Center of South India Mukundapai, Malathi Sharma, Neelam Patil, Akkamahadevi Gopal, Champaka J Cytol Original Article BACKGROUND: Fine-needle aspiration cytology plays role in preoperative diagnosis of any salivary gland mass lesions. Because of heterogeneity of salivary gland lesions and cytomorphology overlap, a uniform 6-tier Milan classification proposed which could be helpful in better communication of reports for patient's management. METHODS: Study included 4 years (2011–2015) retrospective data retrieval from cytology department of our Institute, which is a tertiary care cancer center of South India. Histopathology correlation was done wherever possible. RESULT: Total 253 cases were studied. Histopathological follow-up was available in 115 cases. Cases were categorized as nondiagnostic (1.58%), nonneoplastic (13.43%), benign (30%), atypia (0.8%), and suspicious for malignancy and malignant cytology (51.8%). The risk for malignancy was high for suspicious for malignancy and malignant cytological categories ranged from 96–100%. The sensitivity, specificity, and accuracy for diagnosing malignancy varied from 86.76%, 93.75%, and 89%, respectively. CONCLUSION: Risk stratification approach in classifying salivary gland cytology aspirate as per Milan system provides a standardized reporting and better communication to clinician. Wolters Kluwer - Medknow 2020 2019-12-23 /pmc/articles/PMC6947727/ /pubmed/31942092 http://dx.doi.org/10.4103/JOC.JOC_68_18 Text en Copyright: © 2019 Journal of Cytology http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Mukundapai, Malathi
Sharma, Neelam
Patil, Akkamahadevi
Gopal, Champaka
Fine-Needle Aspiration Cytology of Salivary Gland Lesions: A Revised Classification Based on “Milan System”—4years Experience of Tertiary Care Cancer Center of South India
title Fine-Needle Aspiration Cytology of Salivary Gland Lesions: A Revised Classification Based on “Milan System”—4years Experience of Tertiary Care Cancer Center of South India
title_full Fine-Needle Aspiration Cytology of Salivary Gland Lesions: A Revised Classification Based on “Milan System”—4years Experience of Tertiary Care Cancer Center of South India
title_fullStr Fine-Needle Aspiration Cytology of Salivary Gland Lesions: A Revised Classification Based on “Milan System”—4years Experience of Tertiary Care Cancer Center of South India
title_full_unstemmed Fine-Needle Aspiration Cytology of Salivary Gland Lesions: A Revised Classification Based on “Milan System”—4years Experience of Tertiary Care Cancer Center of South India
title_short Fine-Needle Aspiration Cytology of Salivary Gland Lesions: A Revised Classification Based on “Milan System”—4years Experience of Tertiary Care Cancer Center of South India
title_sort fine-needle aspiration cytology of salivary gland lesions: a revised classification based on “milan system”—4years experience of tertiary care cancer center of south india
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6947727/
https://www.ncbi.nlm.nih.gov/pubmed/31942092
http://dx.doi.org/10.4103/JOC.JOC_68_18
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