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Mepivacaine reduces calcium transients in isolated murine ventricular cardiomyocytes

BACKGROUND: The potential mechanism of mepivacaine’s myocardial depressant effect observed in papillary muscle has not yet been investigated at cellular level. Therefore, we evaluated mepivacaine’s effects on Ca(2+) transient in isolated adult mouse cardiomyocytes. METHODS: Single ventricular myocyt...

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Detalles Bibliográficos
Autores principales: Mosqueira, Matias, Aykut, Güçlü, Fink, Rainer H. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6947945/
https://www.ncbi.nlm.nih.gov/pubmed/31914932
http://dx.doi.org/10.1186/s12871-019-0926-0