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Structural Organization and Dynamics of Homodimeric Cytohesin Family Arf GTPase Exchange Factors in Solution and on Membranes
Membrane dynamic processes require Arf GTPase activation by guanine nucleotide exchange factors (GEFs) with a Sec7 domain. Cytohesin family Arf GEFs function in signaling and cell migration through Arf GTPase activation on the plasma membrane and endosomes. In this study, the structural organization...
Autores principales: | Das, Sanchaita, Malaby, Andrew W., Nawrotek, Agata, Zhang, Wenhua, Zeghouf, Mahel, Maslen, Sarah, Skehel, Mark, Chakravarthy, Srinivas, Irving, Thomas C., Bilsel, Osman, Cherfils, Jacqueline, Lambright, David G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6948192/ https://www.ncbi.nlm.nih.gov/pubmed/31601460 http://dx.doi.org/10.1016/j.str.2019.09.007 |
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