Cargando…

LINC01714 Enhances Gemcitabine Sensitivity by Modulating FOXO3 Phosphorylation in Cholangiocarcinoma

Long noncoding RNAs (lncRNAs) have been shown to play crucial roles in human cancers. However, the underlying biological functions and mechanisms of lncRNAs in cholangiocarcinoma (CCA) remain largely unknown. We aimed to characterize the transcriptional landscape of lncRNAs in CCA and identify lncRN...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shen, Sheng, Wang, Jiwen, Zheng, Bohao, Tao, Ying, Li, Min, Wang, Yueqi, Ni, Xiaoling, Suo, Tao, Liu, Houbao, Liu, Han, Zhang, Jiwei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6948235/ https://www.ncbi.nlm.nih.gov/pubmed/31902744 http://dx.doi.org/10.1016/j.omtn.2019.11.028

Ejemplares similares

Stathmin decreases cholangiocarcinoma cell line sensitivity to staurosporine-triggered apoptosis via the induction of ERK and Akt signaling
por: Wang, Yueqi, et al.
Publicado: (2017)

Tumor-infiltrating mast cells predict prognosis and gemcitabine-based adjuvant chemotherapeutic benefit in biliary tract cancer patients
por: Bo, Xiaobo, et al.
Publicado: (2018)

lncRNA RP11-147L13.8 suppresses metastasis and chemo-resistance by modulating the phosphorylation of c-Jun protein in GBC
por: Zheng, Bohao, et al.
Publicado: (2021)

lncRNA RP11-147L13.8 suppresses metastasis and chemo-resistance by modulating the phosphorylation of c-Jun protein in GBC
por: Zheng, Bohao, et al.
Publicado: (2021)

Biliverdin reductase B impairs cholangiocarcinoma cell motility by inhibiting the Notch/Snail signaling pathway
por: Gao, Zhihui, et al.
Publicado: (2022)

Acetylation stabilizes stathmin1 and promotes its activity contributing to gallbladder cancer metastasis
por: Fan, Kun, et al.
Publicado: (2022)

Preoperative ICG Test to Predict Posthepatectomy Liver Failure and Postoperative Outcomes in Hilar Cholangiocarcinoma
por: Li, Min, et al.
Publicado: (2021)

Serum lipid levels are the risk factors of gallbladder stones: a population-based study in China
por: Wang, Jiwen, et al.
Publicado: (2020)

Laparoscopic common bile duct exploration in patients with previous abdominal biliary tract operations
por: Li, Min, et al.
Publicado: (2020)

Knockdown of SLC39A4 Expression Inhibits the Proliferation and Motility of Gallbladder Cancer Cells and Tumor Formation in Nude Mice
por: Li, Min, et al.
Publicado: (2021)

Tumor‐infiltrating neutrophils predict prognosis and adjuvant chemotherapeutic benefit in patients with biliary cancer
por: Wang, Jie, et al.
Publicado: (2018)

KRAS G12D mutation eliminates reactive oxygen species through the Nrf2/CSE/H (2)S axis and contributes to pancreatic cancer growth : Nrf2/CSE/H (2)S axis decreases ROS in pancreatic cancer
por: Fan, Kun, et al.
Publicado: (2022)

Landscape of distant metastasis mode and current chemotherapy efficacy of the advanced biliary tract cancer in the United States, 2010‐2016
por: Wang, Jie, et al.
Publicado: (2019)

Long non-coding RNA expression profiles in gallbladder carcinoma identified using microarray analysis
por: Wang, Jiwen, et al.
Publicado: (2017)

Potential therapeutic value of primary tumor resection in ampullary cancer patients with distant metastases at initial diagnosis: a population-based study
por: Wang, Jie, et al.
Publicado: (2018)

Long non-coding RNA CRNDE promotes gallbladder carcinoma carcinogenesis and as a scaffold of DMBT1 and C-IAP1 complexes to activating PI3K-AKT pathway
por: Shen, Sheng, et al.
Publicado: (2016)

High infiltration of mast cells is associated with improved response to adjuvant chemotherapy in gallbladder cancer
por: Bo, Xiaobo, et al.
Publicado: (2020)

The impact of preoperative biliary drainage on postoperative outcomes in patients with malignant obstructive jaundice: a retrospective analysis of 290 consecutive cases at a single medical center
por: Gao, Zhihui, et al.
Publicado: (2022)

Low immune index correlates with favorable prognosis but with reduced benefit from chemotherapy in gallbladder cancer
por: Wang, Jie, et al.
Publicado: (2019)

Clinical efficacy of gemcitabine and cisplatin-based transcatheter arterial chemoembolization combined with radiotherapy in hilar cholangiocarcinoma
por: Zheng, Wen-Heng, et al.
Publicado: (2019)

Phosphorylation and acetylation modifications of FOXO3a: Independently or synergistically?
por: Wang, Xianwang, et al.
Publicado: (2017)

Pancreatic ductal adenocarcinoma cells regulated the gemcitabine‐resistance function of CAFs by LINC00460
por: Zhu, Xiao‐Xu, et al.
Publicado: (2022)

BAP1 dependent expression of long non-coding RNA NEAT-1 contributes to sensitivity to gemcitabine in cholangiocarcinoma
por: Parasramka, Mansi, et al.
Publicado: (2017)

Glucose Depletion Enhances the Stem Cell Phenotype and Gemcitabine Resistance of Cholangiocarcinoma Organoids through AKT Phosphorylation and Reactive Oxygen Species
por: Yoshikawa, Nao, et al.
Publicado: (2019)

A redox probe screens MTHFD1 as a determinant of gemcitabine chemoresistance in cholangiocarcinoma
por: Pan, Ruogu, et al.
Publicado: (2021)

Metabolic Phenotyping Predicts Gemcitabine and Cisplatin Chemosensitivity in Patients With Cholangiocarcinoma
por: Suksawat, Manida, et al.
Publicado: (2022)

Downregulation of stathmin 1 in human gallbladder carcinoma inhibits tumor growth in vitro and in vivo
por: Wang, Jiwen, et al.
Publicado: (2016)

Cardamonin Promotes the Apoptosis and Chemotherapy Sensitivity to Gemcitabine of Pancreatic Cancer Through Modulating the FOXO3a-FOXM1 Axis
por: Sun, Huapeng, et al.
Publicado: (2021)

Dual-modality imaging demonstrates the enhanced antitumoral effect of herpes simplex virus-thymidine kinase/ganciclovir plus gemcitabine combination therapy on cholangiocarcinoma
por: WANG, JIANFENG, et al.
Publicado: (2016)

Lapatinib Suppresses HER2-Overexpressed Cholangiocarcinoma and Overcomes ABCB1– Mediated Gemcitabine Chemoresistance
por: Bai, Zhiqing, et al.
Publicado: (2022)

Expression and phosphorylation of FOXO1 influences cell proliferation and apoptosis in the gastrointestinal stromal tumor cell line GIST-T1
por: Wang, Tao, et al.
Publicado: (2018)

Photochemical Internalization of Gemcitabine Is Safe and Effective in Locally Advanced Inoperable Cholangiocarcinoma
por: Trojan, Jörg, et al.
Publicado: (2022)

Down-regulation of LINC00472 promotes osteosarcoma tumorigenesis by reducing FOXO1 expressions via miR-300
por: Zhang, Jingwei, et al.
Publicado: (2020)

Long non-coding RNA LINC00665 promotes gemcitabine resistance of Cholangiocarcinoma cells via regulating EMT and stemness properties through miR-424-5p/BCL9L axis
por: Lu, Min, et al.
Publicado: (2021)

Epigenetic activation of the elongator complex sensitizes gallbladder cancer to gemcitabine therapy
por: Xu, Sunwang, et al.
Publicado: (2021)

LINC01355 suppresses breast cancer growth through FOXO3-mediated transcriptional repression of CCND1
por: Ai, Bolun, et al.
Publicado: (2019)

Overexpression of karyopherin-α2 in cholangiocarcinoma correlates with poor prognosis and gemcitabine sensitivity via nuclear translocation of DNA repair proteins
por: Tsukagoshi, Mariko, et al.
Publicado: (2017)

Key necroptotic proteins are required for Smac mimetic-mediated sensitization of cholangiocarcinoma cells to TNF-α and chemotherapeutic gemcitabine-induced necroptosis
por: Akara-amornthum, Perawatt, et al.
Publicado: (2020)

Modified FOLFIRINOX versus gemcitabine plus oxaliplatin as first-line chemotherapy for patients with locally advanced or metastatic cholangiocarcinoma: a retrospective comparative study
por: Zou, Lu, et al.
Publicado: (2021)

Reversal of Jaundice in Two Patients with Inoperable Cholangiocarcinoma Treated with Cisplatin and Gemcitabine Combination
por: Criel, Maarten, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_o75slecst8keqfg3vbsc998fkt