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Preventive CTLA-4-Ig Treatment Reduces Hepatic Egg Load and Hepatic Fibrosis in Schistosoma mansoni-Infected Mice

BACKGROUND: Hepatic fibrosis and granuloma formation as a consequence of tissue entrapped eggs produced by female schistosomes characterize the pathology of Schistosoma mansoni infection. We have previously shown that single-sex infection with female schistosomes mitigates hepatic fibrosis after sec...

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Detalles Bibliográficos
Autores principales:	Sombetzki, Martina, Rabes, Anne, Bischofsberger, Miriam, Winkelmann, Franziska, Koslowski, Nicole, Schulz, Cindy, Reisinger, Emil C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6948272/ https://www.ncbi.nlm.nih.gov/pubmed/31950032 http://dx.doi.org/10.1155/2019/1704238

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