MicroRNA-106a-3p Induces Apatinib Resistance and Activates Janus-Activated Kinase 2 (JAK2)/Signal Transducer and Activator of Transcription 3 (STAT3) by Targeting the SOCS System in Gastric Cancer

BACKGROUND: MicroRNA (miR)-106a was involved in the tumorigenesis and highly expressed in gastric cancer. Required apatinib resistance greatly limits its efficacy in patients. Thus, the aim of the present study was to investigate the potential role of miR-106a-3p in gastric cancer cells with apatini...

Descripción completa

Detalles Bibliográficos
Autores principales: Guo, Wei, Li, Wenyuan, Yuan, Li, Mei, Xianghuang, Hu, Wenqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2019
Materias:
Lab/In Vitro Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6948289/
https://www.ncbi.nlm.nih.gov/pubmed/31884511
http://dx.doi.org/10.12659/MSM.919610

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6948289/
https://www.ncbi.nlm.nih.gov/pubmed/31884511
http://dx.doi.org/10.12659/MSM.919610

Ejemplares similares