Cargando…

Serum Carnosinase-1 and Albuminuria Rather than the CNDP1 Genotype Correlate with Urinary Carnosinase-1 in Diabetic and Nondiabetic Patients with Chronic Kidney Disease

BACKGROUND: Carnosinase-1 (CN-1) can be detected in 24 h urine of healthy individuals and patients with type 2 diabetes (T2DM). We aimed to assess whether urinary CN-1 is also reliably measured in spot urine and investigated its association with renal function and the albumin/creatinine ratio (ACR)....

Descripción completa

Detalles Bibliográficos
Autores principales:	Rodriguez-Niño, Angelica, Hauske, Sibylle J., Herold, Anna, Qiu, Jiedong, van den Born, Jacob, Bakker, Stephan J. L., Krämer, Bernhard K., Yard, Benito A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6948305/ https://www.ncbi.nlm.nih.gov/pubmed/31950064 http://dx.doi.org/10.1155/2019/6850628

Ejemplares similares

Human carnosinase 1 overexpression aggravates diabetes and renal impairment in BTBR(Ob/Ob) mice
por: Qiu, Jiedong, et al.
Publicado: (2020)

Monoclonal Antibody RYSK173 Recognizes the Dinuclear Zn Center of Serum Carnosinase 1 (CN-1): Possible Consequences of Zn Binding for CN-1 Recognition by RYSK173
por: Zhang, Shiqi, et al.
Publicado: (2016)

Serum and urinary carnosinase-1 correlate with kidney function and inflammation
por: Zhang, Shiqi, et al.
Publicado: (2022)

Correction: Monoclonal Antibody RYSK173 Recognizes the Dinuclear Zn Center of Serum Carnosinase 1 (CN-1): Possible Consequences of Zn Binding for CN-1 Recognition by RYSK173
por: Zhang, Shiqi, et al.
Publicado: (2017)

Association Between Serum Carnosinase Concentration and Activity and Renal Function Impairment in a Type-2 Diabetes Cohort
por: Qiu, Jiedong, et al.
Publicado: (2022)

Carnosinases, Their Substrates and Diseases
por: Bellia, Francesco, et al.
Publicado: (2014)

N-Glycosylation of Carnosinase Influences Protein Secretion and Enzyme Activity: Implications for Hyperglycemia
por: Riedl, Eva, et al.
Publicado: (2010)

Exclusion of Polymorphisms in Carnosinase Genes (CNDP1 and CNDP2) as a Cause of Diabetic Nephropathy in Type 1 Diabetes: Results of Large Case-Control and Follow-Up Studies
por: Wanic, Krzysztof, et al.
Publicado: (2008)

Correlation between serum carnosinase concentration and renal damage in diabetic nephropathy patients
por: Zhou, Zhou, et al.
Publicado: (2021)

Urinary Carnosinase-1 Excretion is Associated with Urinary Carnosine Depletion and Risk of Graft Failure in Kidney Transplant Recipients: Results of the TransplantLines Cohort Study
por: Rodriguez-Niño, Angelica, et al.
Publicado: (2021)

A polymorphism in the gene encoding carnosinase (CNDP1) as a predictor of mortality and progression from nephropathy to end-stage renal disease in type 1 diabetes mellitus
por: Alkhalaf, A., et al.
Publicado: (2010)

The CNDP1 (CTG)(5) Polymorphism Is Associated with Biopsy-Proven Diabetic Nephropathy, Time on Hemodialysis, and Diabetes Duration
por: Albrecht, Thomas, et al.
Publicado: (2017)

Binding Modes of Carnostatine, Homocarnosine, and Ophidine to Human Carnosinase 1
por: Toviwek, Borvornwat, et al.
Publicado: (2023)

Allosteric inhibition of carnosinase (CN1) by inducing a conformational shift
por: Peters, Verena, et al.
Publicado: (2017)

Brain type carnosinase in dementia: a pilot study
por: Balion, Cynthia M, et al.
Publicado: (2007)

Erythrocytes Prevent Degradation of Carnosine by Human Serum Carnosinase
por: Oppermann, Henry, et al.
Publicado: (2021)

Acute balenine supplementation in humans as a natural carnosinase-resistant alternative to carnosine
por: de Jager, Sarah, et al.
Publicado: (2023)

Carnosinase-1 Knock-Out Reduces Kidney Fibrosis in Type-1 Diabetic Mice on High Fat Diet
por: Pfeffer, Tilman, et al.
Publicado: (2023)

Genotype Distribution of CNDP1 Polymorphisms in the Healthy Chinese Han Population: Association with HbA1c and Fasting Blood Glucose
por: Zhang, Shiqi, et al.
Publicado: (2020)

Hyperglycemia Does Not Affect Iron Mediated Toxicity of Cultured Endothelial and Renal Tubular Epithelial Cells: Influence of L-Carnosine
por: Zhang, Shiqi, et al.
Publicado: (2016)

Association Between CNDP1 Genotype and Diabetic Nephropathy Is Sex Specific
por: Mooyaart, Antien L., et al.
Publicado: (2010)

Methylglyoxal induces p53 activation and inhibits mTORC1 in human umbilical vein endothelial cells
por: Zhang, Xinmiao, et al.
Publicado: (2021)

Methylglyoxal down-regulates the expression of cell cycle associated genes and activates the p53 pathway in human umbilical vein endothelial cells
por: Braun, Jana D., et al.
Publicado: (2019)

Carnosine Attenuates the Development of both Type 2 Diabetes and Diabetic Nephropathy in BTBR ob/ob Mice
por: Albrecht, Thomas, et al.
Publicado: (2017)

The (CTG)(n) repeat polymorphism in CNDP1 gene: new insights into an old molecule
por: Santos, Kátia G.
Publicado: (2016)

Lipopolysaccharide Tolerance in Human Primary Monocytes and Polarized Macrophages
por: Li, Hui, et al.
Publicado: (2023)

Association of CTG repeat polymorphism in carnosine dipeptidase 1 (CNDP1) gene with diabetic nephropathy in north Indians
por: Yadav, Ashok K., et al.
Publicado: (2016)

Up-regulation of CNDP2 facilitates the proliferation of colon cancer
por: Xue, Conglong, et al.
Publicado: (2014)

Mild Albuminuria Is a Risk Factor for Faster GFR Decline in the Nondiabetic Population
por: Melsom, Toralf, et al.
Publicado: (2018)

Albuminuria Is Associated with Open-Angle Glaucoma in Nondiabetic Korean Subjects: A Cross-Sectional Study
por: Kim, Gyu Ah, et al.
Publicado: (2016)

The Influence of a Single Nucleotide Polymorphism within CNDP1 on Susceptibility to Diabetic Nephropathy in Japanese Women with Type 2 Diabetes
por: Kurashige, Mahiro, et al.
Publicado: (2013)

Multi-omics of NET formation and correlations with CNDP1, PSPB, and L-cystine levels in severe and mild COVID-19 infections
por: Bramer, Lisa M., et al.
Publicado: (2023)

Glycated Hemoglobin is Independently Associated with Albuminuria in Young Nondiabetic People with Obesity: A Cross-Sectional Study
por: Li, Yanli, et al.
Publicado: (2017)

Kidney disease progression and all-cause mortality across estimated glomerular filtration rate and albuminuria categories among patients with vs. without type 2 diabetes
por: Nichols, Gregory A., et al.
Publicado: (2020)

CNDP1, NOS3, and MnSOD Polymorphisms as Risk Factors for Diabetic Nephropathy among Type 2 Diabetic Patients in Malaysia
por: Yahya, Mohd Jokha, et al.
Publicado: (2019)

A Global Cndp1-Knock-Out Selectively Increases Renal Carnosine and Anserine Concentrations in an Age- and Gender-Specific Manner in Mice
por: Weigand, Tim, et al.
Publicado: (2020)

Correction to: Kidney disease progression and all-cause mortality across estimated glomerular filtration rate and albuminuria categories among patients with vs. without type 2 diabetes
por: Nichols, Gregory A., et al.
Publicado: (2020)

MEA-CNDP: A Membrane Evolutionary Algorithm for Solving Biobjective Critical Node Detection Problem
por: Xu, Yaochang, et al.
Publicado: (2021)

Astragaloside IV Attenuates Programmed Death-Ligand 1-Mediated Immunosuppression during Liver Cancer Development via the miR-135b-5p/CNDP1 Axis
por: Ma, Yang, et al.
Publicado: (2023)

CNDP2 Acts as an Activator for Human Ovarian Cancer Growth and Metastasis via the PI3K/AKT Pathway
por: Zhang, Li Q., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_rm560juh5dndcs9ik81cjmo1mo