Cargando…

Peroxiredoxin 6 Is a Key Antioxidant Enzyme in Modulating the Link between Glycemic and Lipogenic Metabolism

Insulin action and often glucose-stimulated insulin secretion are reduced in obesity. In addition, the excessive intake of lipids increases oxidative stress leading to overt type 2 diabetes mellitus (T2DM). Among the antioxidative defense systems, peroxiredoxin 6 (PRDX6) is able to reduce H(2)O(2) a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Arriga, Roberto, Pacifici, Francesca, Capuani, Barbara, Coppola, Andrea, Orlandi, Augusto, Scioli, Maria Giovanna, Pastore, Donatella, Andreadi, Aikaterini, Sbraccia, Paolo, Tesauro, Manfredi, Daniele, Nicola Di, Sconocchia, Giuseppe, Donadel, Giulia, Bellia, Alfonso, Della-Morte, David, Lauro, Davide
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6948322/ https://www.ncbi.nlm.nih.gov/pubmed/31949886 http://dx.doi.org/10.1155/2019/9685607

Ejemplares similares

Peroxiredoxin 6 Modulates Insulin Secretion and Beta Cell Death via a Mitochondrial Dynamic Network
por: Pacifici, Francesca, et al.
Publicado: (2022)

Prdx6 Plays a Main Role in the Crosstalk between Aging and Metabolic Sarcopenia
por: Pacifici, Francesca, et al.
Publicado: (2020)

Activation of Peripheral Blood Mononuclear Cells and Leptin Secretion: New Potential Role of Interleukin-2 and High Mobility Group Box (HMGB)1
por: Coppola, Andrea, et al.
Publicado: (2021)

Insulin and Exendin-4 Reduced Mutated Huntingtin Accumulation in Neuronal Cells
por: Rea, Silvia, et al.
Publicado: (2020)

SGK-1 protects kidney cells against apoptosis induced by ceramide and TNF-α
por: Pastore, D, et al.
Publicado: (2015)

The Protective Effect of a Unique Mix of Polyphenols and Micronutrients against Neurodegeneration Induced by an In Vitro Model of Parkinson’s Disease
por: Pacifici, Francesca, et al.
Publicado: (2022)

FGF-2b and h-PL Transform Duct and Non-Endocrine Human Pancreatic Cells into Endocrine Insulin Secreting Cells by Modulating Differentiating Genes
por: Donadel, Giulia, et al.
Publicado: (2017)

Recent Pharmacological Options in Type 2 Diabetes and Synergic Mechanism in Cardiovascular Disease
por: Andreadi, Aikaterini, et al.
Publicado: (2023)

The Impact of Vegan Diet in the Prevention and Treatment of Type 2 Diabetes: A Systematic Review
por: Pollakova, Daniela, et al.
Publicado: (2021)

Tyrosol May Prevent Obesity by Inhibiting Adipogenesis in 3T3-L1 Preadipocytes
por: Pacifici, Francesca, et al.
Publicado: (2020)

Polyphenols and Ischemic Stroke: Insight into One of the Best Strategies for Prevention and Treatment
por: Pacifici, Francesca, et al.
Publicado: (2021)

Glucagon Like Peptide 1 and MicroRNA in Metabolic Diseases: Focusing on GLP1 Action on miRNAs
por: Capuani, Barbara, et al.
Publicado: (2018)

P16. Differential susceptibility of human and mouse NK cells to malignant cell-induced abnormalities in autologous combinations: a potential mechanism for the NK cell-based immunotherapy efficacy
por: Sconocchia, G, et al.
Publicado: (2014)

Sildenafil Reduces Insulin-Resistance in Human Endothelial Cells
por: Mammi, Caterina, et al.
Publicado: (2011)

Proposed Tandem Effect of Physical Activity and Sirtuin 1 and 3 Activation in Regulating Glucose Homeostasis
por: Pacifici, Francesca, et al.
Publicado: (2019)

The New Role of SGLT2 Inhibitors in the Management of Heart Failure: Current Evidence and Future Perspective
por: Muscoli, Saverio, et al.
Publicado: (2022)

A Novel Mix of Polyphenols and Micronutrients Reduces Adipogenesis and Promotes White Adipose Tissue Browning via UCP1 Expression and AMPK Activation
por: Pacifici, Francesca, et al.
Publicado: (2023)

Age-Dependent Levels of Protein Kinase Cs in Brain: Reduction of Endogenous Mechanisms of Neuroprotection
por: Pastore, Donatella, et al.
Publicado: (2019)

Geographic and Ethnic Inequalities in Diabetes-Related Amputations
por: Bellia, Alfonso, et al.
Publicado: (2022)

Enhancement of anti-leukemia activity of NK cells in vitro and in vivo by inhibition of leukemia cell-induced NK cell damage
por: Arriga, Roberto, et al.
Publicado: (2015)

Prevalence and risk of new-onset diabetes mellitus after COVID-19: a systematic review and meta-analysis
por: Bellia, Chiara, et al.
Publicado: (2023)

Peripheral Blood Mononuclear Cells: A New Frontier in the Management of Patients with Diabetes and No-Option Critical Limb Ischaemia
por: Meloni, Marco, et al.
Publicado: (2023)

Insulin Resistance and Acne: The Role of Metformin as Alternative Therapy in Men
por: Andreadi, Aikaterini, et al.
Publicado: (2022)

FCγ Chimeric Receptor-Engineered T Cells: Methodology, Advantages, Limitations, and Clinical Relevance
por: Caratelli, Sara, et al.
Publicado: (2017)

NK Cell Inflammation in the Clinical Outcome of Colorectal Carcinoma
por: Coppola, Andrea, et al.
Publicado: (2015)

The Role of Perivascular Adipose Tissue in the Pathogenesis of Endothelial Dysfunction in Cardiovascular Diseases and Type 2 Diabetes Mellitus
por: Valentini, Alessia, et al.
Publicado: (2023)

Drug interactions of direct oral anticoagulants in elderly patients with cardiometabolic diseases
por: Bellia, Alfonso, et al.
Publicado: (2021)

Sirtuins and Cancer: Role in the Epithelial-Mesenchymal Transition
por: Palmirotta, Raffaele, et al.
Publicado: (2016)

The Neuro-Ischaemic Charcot Foot: Prevalence, Characteristics and Severity of Peripheral Arterial Disease in Acute Charcot Neuro-Arthropathy
por: Meloni, Marco, et al.
Publicado: (2022)

Nature can still be the strongest help against aging and neurodegeneration: the sirtuins way
por: Della-Morte, David, et al.
Publicado: (2022)

Surgical treatment of post-menopausal ovarian hyperandrogenism improves glucometabolic profile alongside clinical hirsutism
por: De Taddeo, Sofia, et al.
Publicado: (2023)

Metabolic and Cardiovascular Effects of Ghrelin
por: Tesauro, Manfredi, et al.
Publicado: (2010)

Unique Mode of Lipogenic Activation in Rat Preputial Sebocytes
por: Deplewski, Dianne, et al.
Publicado: (2011)

Lipogenic gene expression profile in patients with gastric cancer
por: MIYACHI, KAZUHITO, et al.
Publicado: (2013)

Insulin-Related Lipohypertrophy: Lipogenic Action or Tissue Trauma?
por: Barola, Anjana, et al.
Publicado: (2018)

Lipogenic effects of androgen signaling in normal and malignant prostate
por: Mah, Chui Yan, et al.
Publicado: (2020)

Measurement of lipogenic flux by deuterium resolved mass spectrometry
por: Fu, Xiaorong, et al.
Publicado: (2021)

Overview on Peroxiredoxin
por: Rhee, Sue Goo
Publicado: (2016)

Association of Gut Hormones and Microbiota with Vascular Dysfunction in Obesity
por: Rovella, Valentina, et al.
Publicado: (2021)

Lipogenic metabolism: a viable target for prostate cancer treatment?
por: Liang, Mengmeng, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_b9ago0m658gl5orm6al35lh4bu