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GABA-A receptor modulating steroids in acute and chronic stress; relevance for cognition and dementia?
Cognitive dysfunction, dementia and Alzheimer's disease (AD) are increasing as the population worldwide ages. Therapeutics for these conditions is an unmet need. This review focuses on the role of the positive GABA-A receptor modulating steroid allopregnanolone (APα), it's role in underlyi...
Autores principales: | Bengtsson, S.K.S., Bäckström, T., Brinton, R., Irwin, R.W., Johansson, M., Sjöstedt, J., Wang, M.D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6948369/ https://www.ncbi.nlm.nih.gov/pubmed/31921942 http://dx.doi.org/10.1016/j.ynstr.2019.100206 |
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