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Associating lncRNAs with small molecules via bilevel optimization reveals cancer-related lncRNAs

Long noncoding RNA (lncRNA) transcripts have emerging impacts in cancer studies, which suggests their potential as novel therapeutic agents. However, the molecular mechanism behind their treatment effects is still unclear. Here, we designed a computational model to Associate LncRNAs with Anti-Cancer...

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Detalles Bibliográficos
Autores principales: Wang, Yongcui, Chen, Shilong, Chen, Luonan, Wang, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6948815/
https://www.ncbi.nlm.nih.gov/pubmed/31877126
http://dx.doi.org/10.1371/journal.pcbi.1007540