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Aspergillus fumigatus calcium-responsive transcription factors regulate cell wall architecture promoting stress tolerance, virulence and caspofungin resistance

Aspergillus fumigatus causes invasive aspergillosis, the most common life-threatening fungal disease of immuno-compromised humans. The treatment of disseminated infections with antifungal drugs, including echinocandin cell wall biosynthesis inhibitors, is increasingly challenging due to the rise of...

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Detalles Bibliográficos
Autores principales: de Castro, Patrícia Alves, Colabardini, Ana Cristina, Manfiolli, Adriana Oliveira, Chiaratto, Jéssica, Silva, Lilian Pereira, Mattos, Eliciane Cevolani, Palmisano, Giuseppe, Almeida, Fausto, Persinoti, Gabriela Felix, Ries, Laure Nicolas Annick, Mellado, Laura, Rocha, Marina Campos, Bromley, Michael, Silva, Roberto Nascimento, de Souza, Gabriel Scalini, Loures, Flávio Vieira, Malavazi, Iran, Brown, Neil Andrew, Goldman, Gustavo H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6948819/
https://www.ncbi.nlm.nih.gov/pubmed/31887136
http://dx.doi.org/10.1371/journal.pgen.1008551