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Small Centers with Big Ventures: Autologous Stem Cell Transplantation Survival Data

We present the first-ever autologous stem cell transplantation (ASCT) outcome data from a secondary-care healthcare facility. Albeit exact details of patient and disease characteristics and co-morbidity scores for all patients are not available, the engraftment and survival data is very similar to t...

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Detalles Bibliográficos
Autores principales: Abid, Muhammad Bilal, Mughal, Mustafa, Babbra, Ranjeet, Abid, Muhammad Abbas, Blesing, Norbert, Anwer, Saiyed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: West Asia Organization for Cancer Prevention 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6948904/
https://www.ncbi.nlm.nih.gov/pubmed/31030464
http://dx.doi.org/10.31557/APJCP.2019.20.4.987
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author Abid, Muhammad Bilal
Mughal, Mustafa
Babbra, Ranjeet
Abid, Muhammad Abbas
Blesing, Norbert
Anwer, Saiyed
author_facet Abid, Muhammad Bilal
Mughal, Mustafa
Babbra, Ranjeet
Abid, Muhammad Abbas
Blesing, Norbert
Anwer, Saiyed
author_sort Abid, Muhammad Bilal
collection PubMed
description We present the first-ever autologous stem cell transplantation (ASCT) outcome data from a secondary-care healthcare facility. Albeit exact details of patient and disease characteristics and co-morbidity scores for all patients are not available, the engraftment and survival data is very similar to those published from large tertiary-care cancer centres, both regionally and internationally. Transplant Related Mortality (TRM) of 3.1% is within the expected range and includes a patient who died of acute drug reaction (ADR) during conditioning chemotherapy, prior to the ASCT. Furthermore, cyclophosphamide mobilization chemotherapy is given in the outpatient setting. This study is important in terms of healthcare resource optimization as well as patients’ convenience and highlights that ASCT can be performed in a safe and effective manner with comparable survival rates even at a DGH, provided the centre stays abreast with the recent developments and can offer its patients with standard of care treatment of the era.
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spelling pubmed-69489042020-02-04 Small Centers with Big Ventures: Autologous Stem Cell Transplantation Survival Data Abid, Muhammad Bilal Mughal, Mustafa Babbra, Ranjeet Abid, Muhammad Abbas Blesing, Norbert Anwer, Saiyed Asian Pac J Cancer Prev Short Communication We present the first-ever autologous stem cell transplantation (ASCT) outcome data from a secondary-care healthcare facility. Albeit exact details of patient and disease characteristics and co-morbidity scores for all patients are not available, the engraftment and survival data is very similar to those published from large tertiary-care cancer centres, both regionally and internationally. Transplant Related Mortality (TRM) of 3.1% is within the expected range and includes a patient who died of acute drug reaction (ADR) during conditioning chemotherapy, prior to the ASCT. Furthermore, cyclophosphamide mobilization chemotherapy is given in the outpatient setting. This study is important in terms of healthcare resource optimization as well as patients’ convenience and highlights that ASCT can be performed in a safe and effective manner with comparable survival rates even at a DGH, provided the centre stays abreast with the recent developments and can offer its patients with standard of care treatment of the era. West Asia Organization for Cancer Prevention 2019 /pmc/articles/PMC6948904/ /pubmed/31030464 http://dx.doi.org/10.31557/APJCP.2019.20.4.987 Text en This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Short Communication
Abid, Muhammad Bilal
Mughal, Mustafa
Babbra, Ranjeet
Abid, Muhammad Abbas
Blesing, Norbert
Anwer, Saiyed
Small Centers with Big Ventures: Autologous Stem Cell Transplantation Survival Data
title Small Centers with Big Ventures: Autologous Stem Cell Transplantation Survival Data
title_full Small Centers with Big Ventures: Autologous Stem Cell Transplantation Survival Data
title_fullStr Small Centers with Big Ventures: Autologous Stem Cell Transplantation Survival Data
title_full_unstemmed Small Centers with Big Ventures: Autologous Stem Cell Transplantation Survival Data
title_short Small Centers with Big Ventures: Autologous Stem Cell Transplantation Survival Data
title_sort small centers with big ventures: autologous stem cell transplantation survival data
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6948904/
https://www.ncbi.nlm.nih.gov/pubmed/31030464
http://dx.doi.org/10.31557/APJCP.2019.20.4.987
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