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DNA-dependent protein kinase promotes DNA end processing by MRN and CtIP

The repair of DNA double-strand breaks occurs through nonhomologous end joining or homologous recombination in vertebrate cells—a choice that is thought to be decided by a competition between DNA-dependent protein kinase (DNA-PK) and the Mre11/Rad50/Nbs1 (MRN) complex but is not well understood. Usi...

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Detalles Bibliográficos
Autores principales:	Deshpande, Rajashree A., Myler, Logan R., Soniat, Michael M., Makharashvili, Nodar, Lee, Linda, Lees-Miller, Susan P., Finkelstein, Ilya J., Paull, Tanya T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2020
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949041/ https://www.ncbi.nlm.nih.gov/pubmed/31934630 http://dx.doi.org/10.1126/sciadv.aay0922

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