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Suppression of protein degradation by leucine requires its conversion to β-hydroxy-β-methyl butyrate in C2C12 myotubes

The aims of this study were to investigate whether the inhibitory effect of Leucine (Leu) on starvation-induced protein degradation was mediated by its metabolite β-hydroxy-β-methyl butyrate (HMB), and to explore the mechanisms involved. The results showed that the beneficial effects of Leu on prote...

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Detalles Bibliográficos
Autores principales:	Duan, Yehui, Zhong, Yinzhao, Song, Bo, Zheng, Changbing, Xu, Kang, Kong, Xiangfeng, Li, Fengna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2019
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949090/ https://www.ncbi.nlm.nih.gov/pubmed/31881014 http://dx.doi.org/10.18632/aging.102509

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