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Suppression of FADS1 induces ROS generation, cell cycle arrest, and apoptosis in melanocytes: implications for vitiligo

Vitiligo is a potentially serious condition characterized by loss of melanin and death of melanocytes. To identify potential therapeutic targets for vitiligo, we conducted a microarray analysis of three human vitiligo specimens and paired adjacent normal tissues. Because we found that the fatty acid...

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Detalles Bibliográficos
Autores principales: Tang, Luyan, Li, Jian, Fu, Wenwen, Wu, Wenyu, Xu, Jinhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949104/
https://www.ncbi.nlm.nih.gov/pubmed/31866583
http://dx.doi.org/10.18632/aging.102452