Ultrahigh Resolution Polarization Sensitive Optical Coherence Tomography of the Human Cornea with Conical Scanning Pattern and Variable Dispersion Compensation

Noninvasive corneal imaging is essential for the diagnosis and treatment control of various diseases affecting the anterior segment of the eye. This study presents an ultrahigh resolution polarization sensitive optical coherence tomography instrument operating in the 840 nm wavelength band that inco...

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Autores principales: Beer, Florian, Patil, Rahul P., Sinha-Roy, Abhijit, Baumann, Bernhard, Pircher, Michael, Hitzenberger, Christoph K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949131/
https://www.ncbi.nlm.nih.gov/pubmed/31915537
http://dx.doi.org/10.3390/app9204245
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author Beer, Florian
Patil, Rahul P.
Sinha-Roy, Abhijit
Baumann, Bernhard
Pircher, Michael
Hitzenberger, Christoph K.
author_facet Beer, Florian
Patil, Rahul P.
Sinha-Roy, Abhijit
Baumann, Bernhard
Pircher, Michael
Hitzenberger, Christoph K.
author_sort Beer, Florian
collection PubMed
description Noninvasive corneal imaging is essential for the diagnosis and treatment control of various diseases affecting the anterior segment of the eye. This study presents an ultrahigh resolution polarization sensitive optical coherence tomography instrument operating in the 840 nm wavelength band that incorporates a conical scanning design for large field of view imaging of the cornea. As the conical scanning introduces a dispersion mismatch depending on the scanning angle, this study implemented variable, location dependent, numerical dispersion compensation in order to achieve high axial resolution throughout the imaged volume. The corneal images were recorded in vivo in healthy volunteers showing various details of corneal structures.
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spelling pubmed-69491312020-01-08 Ultrahigh Resolution Polarization Sensitive Optical Coherence Tomography of the Human Cornea with Conical Scanning Pattern and Variable Dispersion Compensation Beer, Florian Patil, Rahul P. Sinha-Roy, Abhijit Baumann, Bernhard Pircher, Michael Hitzenberger, Christoph K. Appl Sci (Basel) Article Noninvasive corneal imaging is essential for the diagnosis and treatment control of various diseases affecting the anterior segment of the eye. This study presents an ultrahigh resolution polarization sensitive optical coherence tomography instrument operating in the 840 nm wavelength band that incorporates a conical scanning design for large field of view imaging of the cornea. As the conical scanning introduces a dispersion mismatch depending on the scanning angle, this study implemented variable, location dependent, numerical dispersion compensation in order to achieve high axial resolution throughout the imaged volume. The corneal images were recorded in vivo in healthy volunteers showing various details of corneal structures. 2019-10-11 2019-10 /pmc/articles/PMC6949131/ /pubmed/31915537 http://dx.doi.org/10.3390/app9204245 Text en http://creativecommons.org/licenses/by/4.0/ This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Beer, Florian
Patil, Rahul P.
Sinha-Roy, Abhijit
Baumann, Bernhard
Pircher, Michael
Hitzenberger, Christoph K.
Ultrahigh Resolution Polarization Sensitive Optical Coherence Tomography of the Human Cornea with Conical Scanning Pattern and Variable Dispersion Compensation
title Ultrahigh Resolution Polarization Sensitive Optical Coherence Tomography of the Human Cornea with Conical Scanning Pattern and Variable Dispersion Compensation
title_full Ultrahigh Resolution Polarization Sensitive Optical Coherence Tomography of the Human Cornea with Conical Scanning Pattern and Variable Dispersion Compensation
title_fullStr Ultrahigh Resolution Polarization Sensitive Optical Coherence Tomography of the Human Cornea with Conical Scanning Pattern and Variable Dispersion Compensation
title_full_unstemmed Ultrahigh Resolution Polarization Sensitive Optical Coherence Tomography of the Human Cornea with Conical Scanning Pattern and Variable Dispersion Compensation
title_short Ultrahigh Resolution Polarization Sensitive Optical Coherence Tomography of the Human Cornea with Conical Scanning Pattern and Variable Dispersion Compensation
title_sort ultrahigh resolution polarization sensitive optical coherence tomography of the human cornea with conical scanning pattern and variable dispersion compensation
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949131/
https://www.ncbi.nlm.nih.gov/pubmed/31915537
http://dx.doi.org/10.3390/app9204245
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