Nicotinamide Riboside Enhances Mitochondrial Proteostasis and Adult Neurogenesis through Activation of Mitochondrial Unfolded Protein Response Signaling in the Brain of ALS SOD1(G93A) Mice

Amyotrophic lateral sclerosis (ALS) is caused by the progressive degeneration of motor neurons in the spinal cord, the brain stem, and the motor cortex. So far, there is still a lack of effective drugs. Nicotinamide adenine dinucleotide (NAD+) takes part in redox reactions and the NAD-dependent sign...

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Detalles Bibliográficos
Autores principales: Zhou, Qi, Zhu, Lei, Qiu, Weiwen, Liu, Yue, Yang, Fang, Chen, Wenzhi, Xu, Renshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949147/
https://www.ncbi.nlm.nih.gov/pubmed/31929756
http://dx.doi.org/10.7150/ijbs.38487

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