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A rare case of perivascular epithelioid cell tumor (PEComa) of the pancreas diagnosed by endoscopic ultrasound

A 49-year-old woman consulted her general practitioner (GP) regarding epigastric pain that she had experienced for 2 months. Physical examination and laboratory results were unremarkable. An abdominal ultrasound indicated a solid pancreatic tumor, which was confirmed on subsequent CT and MRI. Endosc...

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Autores principales: Ulrich, J. D., Specht, K., Schlitter, A. M., Ceyhan, G. O., Quante, M., Schmid, R. M., Schlag, C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: © Georg Thieme Verlag KG 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949164/
https://www.ncbi.nlm.nih.gov/pubmed/31921981
http://dx.doi.org/10.1055/a-1038-3852
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author Ulrich, J. D.
Specht, K.
Schlitter, A. M.
Ceyhan, G. O.
Quante, M.
Schmid, R. M.
Schlag, C.
author_facet Ulrich, J. D.
Specht, K.
Schlitter, A. M.
Ceyhan, G. O.
Quante, M.
Schmid, R. M.
Schlag, C.
author_sort Ulrich, J. D.
collection PubMed
description A 49-year-old woman consulted her general practitioner (GP) regarding epigastric pain that she had experienced for 2 months. Physical examination and laboratory results were unremarkable. An abdominal ultrasound indicated a solid pancreatic tumor, which was confirmed on subsequent CT and MRI. Endoscopic ultrasound (EUS) showed a well-defined heterogeneous, predominantly hypoechoic mass in the pancreatic body, so a neuroendocrine tumor (NET) was suspected. However, EUS-guided fine-needle aspiration (EUS-FNA) was performed and based on (immuno-)histochemical findings, the extremely rare diagnosis of a perivascular epithelioid cell tumor (PEComa) of the pancreas was made. Due to the malignant potential of pancreatic PEComas, laparoscopic left-sided pancreatectomy was performed. We present a case diagnosed by preoperative EUS-FNA highlighting the clinical and endosonographic features which help to distinguish it from its most important differential diagnosis, neuroendocrine tumors (NETs) of the pancreas.
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spelling pubmed-69491642020-01-09 A rare case of perivascular epithelioid cell tumor (PEComa) of the pancreas diagnosed by endoscopic ultrasound Ulrich, J. D. Specht, K. Schlitter, A. M. Ceyhan, G. O. Quante, M. Schmid, R. M. Schlag, C. Endosc Int Open A 49-year-old woman consulted her general practitioner (GP) regarding epigastric pain that she had experienced for 2 months. Physical examination and laboratory results were unremarkable. An abdominal ultrasound indicated a solid pancreatic tumor, which was confirmed on subsequent CT and MRI. Endoscopic ultrasound (EUS) showed a well-defined heterogeneous, predominantly hypoechoic mass in the pancreatic body, so a neuroendocrine tumor (NET) was suspected. However, EUS-guided fine-needle aspiration (EUS-FNA) was performed and based on (immuno-)histochemical findings, the extremely rare diagnosis of a perivascular epithelioid cell tumor (PEComa) of the pancreas was made. Due to the malignant potential of pancreatic PEComas, laparoscopic left-sided pancreatectomy was performed. We present a case diagnosed by preoperative EUS-FNA highlighting the clinical and endosonographic features which help to distinguish it from its most important differential diagnosis, neuroendocrine tumors (NETs) of the pancreas. © Georg Thieme Verlag KG 2020-01 2020-01-08 /pmc/articles/PMC6949164/ /pubmed/31921981 http://dx.doi.org/10.1055/a-1038-3852 Text en https://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License, which permits unrestricted reproduction and distribution, for non-commercial purposes only; and use and reproduction, but not distribution, of adapted material for non-commercial purposes only, provided the original work is properly cited.
spellingShingle Ulrich, J. D.
Specht, K.
Schlitter, A. M.
Ceyhan, G. O.
Quante, M.
Schmid, R. M.
Schlag, C.
A rare case of perivascular epithelioid cell tumor (PEComa) of the pancreas diagnosed by endoscopic ultrasound
title A rare case of perivascular epithelioid cell tumor (PEComa) of the pancreas diagnosed by endoscopic ultrasound
title_full A rare case of perivascular epithelioid cell tumor (PEComa) of the pancreas diagnosed by endoscopic ultrasound
title_fullStr A rare case of perivascular epithelioid cell tumor (PEComa) of the pancreas diagnosed by endoscopic ultrasound
title_full_unstemmed A rare case of perivascular epithelioid cell tumor (PEComa) of the pancreas diagnosed by endoscopic ultrasound
title_short A rare case of perivascular epithelioid cell tumor (PEComa) of the pancreas diagnosed by endoscopic ultrasound
title_sort rare case of perivascular epithelioid cell tumor (pecoma) of the pancreas diagnosed by endoscopic ultrasound
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949164/
https://www.ncbi.nlm.nih.gov/pubmed/31921981
http://dx.doi.org/10.1055/a-1038-3852
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