β3-adrenoreceptor blockade reduces tumor growth and increases neuronal differentiation in neuroblastoma via SK2/S1P(2) modulation

Neuroblastoma (NB) is the most frequently observed among extracranial pediatric solid tumors. It displays an extreme clinical heterogeneity, in particular for the presentation at diagnosis and response to treatment, often depending on cancer cell differentiation/stemness. The frequent presence of el...

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Detalles Bibliográficos
Autores principales: Bruno, Gennaro, Cencetti, Francesca, Pini, Alessandro, Tondo, Annalisa, Cuzzubbo, Daniela, Fontani, Filippo, Strinna, Vanessa, Buccoliero, Anna Maria, Casazza, Gabriella, Donati, Chiara, Filippi, Luca, Bruni, Paola, Favre, Claudio, Calvani, Maura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949192/
https://www.ncbi.nlm.nih.gov/pubmed/31477835
http://dx.doi.org/10.1038/s41388-019-0993-1

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