Molecular regulation of kidney development: is the answer blowing in the Wnt?

Development of the metanephric kidney is a complicated process regulated by reciprocal signals from the ureteric bud and the metanephric mesenchyme that regulate tubule formation and epithelial branching morphogenesis. Over the past several years, several studies have suggested that Wnt signaling is...

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Detalles Bibliográficos
Autores principales: Merkel, Calli E., Karner, Courtney M., Carroll, Thomas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2007
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949197/
https://www.ncbi.nlm.nih.gov/pubmed/17554566
http://dx.doi.org/10.1007/s00467-007-0504-4
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author Merkel, Calli E.
Karner, Courtney M.
Carroll, Thomas J.
author_facet Merkel, Calli E.
Karner, Courtney M.
Carroll, Thomas J.
author_sort Merkel, Calli E.
collection PubMed
description Development of the metanephric kidney is a complicated process regulated by reciprocal signals from the ureteric bud and the metanephric mesenchyme that regulate tubule formation and epithelial branching morphogenesis. Over the past several years, several studies have suggested that Wnt signaling is involved in multiple aspects of normal kidney development as well as injury response and cancer progression. We will review these data here.
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spelling pubmed-69491972020-01-23 Molecular regulation of kidney development: is the answer blowing in the Wnt? Merkel, Calli E. Karner, Courtney M. Carroll, Thomas J. Pediatr Nephrol Review Development of the metanephric kidney is a complicated process regulated by reciprocal signals from the ureteric bud and the metanephric mesenchyme that regulate tubule formation and epithelial branching morphogenesis. Over the past several years, several studies have suggested that Wnt signaling is involved in multiple aspects of normal kidney development as well as injury response and cancer progression. We will review these data here. Springer Berlin Heidelberg 2007-06-07 2007 /pmc/articles/PMC6949197/ /pubmed/17554566 http://dx.doi.org/10.1007/s00467-007-0504-4 Text en © IPNA 2007 This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Review
Merkel, Calli E.
Karner, Courtney M.
Carroll, Thomas J.
Molecular regulation of kidney development: is the answer blowing in the Wnt?
title Molecular regulation of kidney development: is the answer blowing in the Wnt?
title_full Molecular regulation of kidney development: is the answer blowing in the Wnt?
title_fullStr Molecular regulation of kidney development: is the answer blowing in the Wnt?
title_full_unstemmed Molecular regulation of kidney development: is the answer blowing in the Wnt?
title_short Molecular regulation of kidney development: is the answer blowing in the Wnt?
title_sort molecular regulation of kidney development: is the answer blowing in the wnt?
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949197/
https://www.ncbi.nlm.nih.gov/pubmed/17554566
http://dx.doi.org/10.1007/s00467-007-0504-4
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