Rescue of premature aging defects in Cockayne syndrome stem cells by CRISPR/Cas9-mediated gene correction

Cockayne syndrome (CS) is a rare autosomal recessive inherited disorder characterized by a variety of clinical features, including increased sensitivity to sunlight, progressive neurological abnormalities, and the appearance of premature aging. However, the pathogenesis of CS remains unclear due to...

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Detalles Bibliográficos
Autores principales: Wang, Si, Min, Zheying, Ji, Qianzhao, Geng, Lingling, Su, Yao, Liu, Zunpeng, Hu, Huifang, Wang, Lixia, Zhang, Weiqi, Suzuiki, Keiichiro, Huang, Yu, Zhang, Puyao, Tang, Tie-Shan, Qu, Jing, Yu, Yang, Liu, Guang-Hui, Qiao, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Higher Education Press 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949206/
https://www.ncbi.nlm.nih.gov/pubmed/31037510
http://dx.doi.org/10.1007/s13238-019-0623-2

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