IgA subclasses have different effector functions associated with distinct glycosylation profiles

Monomeric serum immunoglobulin A (IgA) can contribute to the development of various autoimmune diseases, but the regulation of serum IgA effector functions is not well defined. Here, we show that the two IgA subclasses (IgA1 and IgA2) differ in their effect on immune cells due to distinct binding an...

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Detalles Bibliográficos
Autores principales: Steffen, Ulrike, Koeleman, Carolien A., Sokolova, Maria V., Bang, Holger, Kleyer, Arnd, Rech, Jürgen, Unterweger, Harald, Schicht, Martin, Garreis, Fabian, Hahn, Jonas, Andes, Fabian T., Hartmann, Fabian, Hahn, Madelaine, Mahajan, Aparna, Paulsen, Friedrich, Hoffmann, Markus, Lochnit, Günter, Muñoz, Luis E., Wuhrer, Manfred, Falck, David, Herrmann, Martin, Schett, Georg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949214/
https://www.ncbi.nlm.nih.gov/pubmed/31913287
http://dx.doi.org/10.1038/s41467-019-13992-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949214/
https://www.ncbi.nlm.nih.gov/pubmed/31913287
http://dx.doi.org/10.1038/s41467-019-13992-8

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