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Maternal high fat diet consumption reduces liver alpha7 nicotinic cholinergic receptor expression and impairs insulin signalling in the offspring

The activation of nicotinic acetylcholine receptor α7 subunit (α7nAChR) has been associated to anti-inflammatory response in macrophages. High-fat diet (HFD) consumption during pregnancy and lactation impairs the cholinergic anti-inflammatory pathway in liver and white adipose tissue of offspring. I...

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Detalles Bibliográficos
Autores principales: Costa, S. O., Souza, C. M., Lanza, P. G., Sartori, J. O., Ignacio-Souza, L. M., Candreva, T., Rodrigues, H. G., Torsoni, A. S., Milanski, M., Torsoni, M. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949221/
https://www.ncbi.nlm.nih.gov/pubmed/31913329
http://dx.doi.org/10.1038/s41598-019-56880-3

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