Characteristics of induced mutations in offspring derived from irradiated mouse spermatogonia and mature oocytes

The exposure of germ cells to radiation introduces mutations in the genomes of offspring, and a previous whole-genome sequencing study indicated that the irradiation of mouse sperm induces insertions/deletions (indels) and multisite mutations (clustered single nucleotide variants and indels). Howeve...

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Detalles Bibliográficos
Autores principales: Satoh, Yasunari, Asakawa, Jun-ichi, Nishimura, Mayumi, Kuo, Tony, Shinkai, Norio, Cullings, Harry M., Minakuchi, Yohei, Sese, Jun, Toyoda, Atsushi, Shimada, Yoshiya, Nakamura, Nori, Uchimura, Arikuni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949229/
https://www.ncbi.nlm.nih.gov/pubmed/31913321
http://dx.doi.org/10.1038/s41598-019-56881-2

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