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Architecture of The Human Ape1 Interactome Defines Novel Cancers Signatures

APE1 is essential in cancer cells due to its central role in the Base Excision Repair pathway of DNA lesions and in the transcriptional regulation of genes involved in tumor progression/chemoresistance. Indeed, APE1 overexpression correlates with chemoresistance in more aggressive cancers, and APE1...

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Detalles Bibliográficos
Autores principales:	Ayyildiz, Dilara, Antoniali, Giulia, D’Ambrosio, Chiara, Mangiapane, Giovanna, Dalla, Emiliano, Scaloni, Andrea, Tell, Gianluca, Piazza, Silvano
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949240/ https://www.ncbi.nlm.nih.gov/pubmed/31913336 http://dx.doi.org/10.1038/s41598-019-56981-z

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