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Nucleophosmin mutations confer an independent favorable prognostic impact in 869 pediatric patients with acute myeloid leukemia

Studies on the clinical significance of Nucleophosmin (NPM1) mutations in pediatric AML in a large cohort are lacking. Moreover, the prognosis of patients with co-occurring NPM1 and FLT3/ITD mutations is controversial. Here, we analyzed the impact of NPM1 mutations on prognoses of 869 pediatric AML...

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Detalles Bibliográficos
Autores principales: Xu, Lu-Hong, Fang, Jian-Pei, Liu, Yao-Chung, Jones, Adrianna I., Chai, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949268/
https://www.ncbi.nlm.nih.gov/pubmed/31915364
http://dx.doi.org/10.1038/s41408-019-0268-7