Repurposing a psychoactive drug for children with cancer: p27(Kip1)-dependent inhibition of metastatic neuroblastomas by Prozac

The MYC family of transcription factors is a major driver of human cancer and potential therapeutic target. However, no clinically viable drugs have been yet developed that are able to directly tackle MYC oncoproteins. In our laboratory, we are exploring alternative approaches aiming to disturb sign...

Descripción completa

Detalles Bibliográficos
Autores principales: Bibbo’, Sandra, Lamolinara, Alessia, Capone, Emily, Purgato, Stefania, Tsakaneli, Alexia, Panella, Valeria, Sallese, Michele, Rossi, Cosmo, Ciufici, Paolo, Nieddu, Valentina, De Laurenzi, Vincenzo, Iezzi, Manuela, Perini, Giovanni, Sala, Gianluca, Sala, Arturo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949307/
https://www.ncbi.nlm.nih.gov/pubmed/31900399
http://dx.doi.org/10.1038/s41389-019-0186-3

Ejemplares similares

Ejemplares similares