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A bacteriophage nucleus-like compartment shields DNA from CRISPR nucleases

All viruses require strategies to inhibit or evade the immunity pathways of cells they infect. The viruses that infect bacteria, bacteriophages (phages), must avoid nucleic-acid targeting immune pathways such as CRISPR-Cas (clustered regularly interspaced short palindromic repeats and CRISPR-associa...

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Detalles Bibliográficos
Autores principales: Mendoza, Senén D., Nieweglowska, Eliza S., Govindarajan, Sutharsan, Leon, Lina M., Berry, Joel D., Tiwari, Anika, Chaikeeratisak, Vorrapon, Pogliano, Joe, Agard, David A., Bondy-Denomy, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949375/
https://www.ncbi.nlm.nih.gov/pubmed/31819262
http://dx.doi.org/10.1038/s41586-019-1786-y