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MRE11A Isoform Expression Associated with Outcome Following Radiotherapy in Muscle-Invasive Bladder Cancer does not Alter Cell Survival and DNA Double-Strand Break Repair Following Ionising Radiation

BACKGROUND: DNA double strand breaks are the cytotoxic lesions produced by ionising radiation. Critical for the repair of these lesions is the DNA damage response protein MRE11 which, in a complex with RAD50 and NBS1, mediates DNA damage signalling and double-strand break repair. We previously found...

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Detalles Bibliográficos
Autores principales:	Walker, Alexandra K., Na, Juri, Browning, Lisa, Humayun-Zakaria, Nada, Zeegers, Maurice P., Cheng, K.K., James, Nicholas D., Bryan, Richard T., Arnold, Roland, Kiltie, Anne E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	IOS Press 2019
Materias:	Research Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949534/ https://www.ncbi.nlm.nih.gov/pubmed/31942442 http://dx.doi.org/10.3233/BLC-190209

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