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Structural and kinetic insights into flavin-containing monooxygenase and calponin-homology domains in human MICAL3

MICAL is an oxidoreductase that participates in cytoskeleton reorganization via actin disassembly in the presence of NADPH. Although three MICALs (MICAL1, MICAL2 and MICAL3) have been identified in mammals, only the structure of mouse MICAL1 has been reported. Here, the first crystal structure of hu...

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Detalles Bibliográficos
Autores principales: Kim, Junsoo, Lee, Haemin, Roh, Yeon Jin, Kim, Han-ul, Shin, Donghyuk, Kim, Sorah, Son, Jonghyeon, Lee, Aro, Kim, Minseo, Park, Junga, Hwang, Seong Yun, Kim, Kyunghwan, Lee, Yong Kwon, Jung, Hyun Suk, Hwang, Kwang Yeon, Lee, Byung Cheon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949599/
https://www.ncbi.nlm.nih.gov/pubmed/31949908
http://dx.doi.org/10.1107/S2052252519015409