Mirolysin structures open a window on gum disease

Guevara, Rodriguez-Banqueri et al. [(2020), IUCrJ, 7, 18–29] determine crystal structures of mirolysin, a metalloprotease that helps oral pathogen Tannerella forsythia evade the human immune response. The structures provide insight into the regulation and specificity of mirolysin, and hint at how it...

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Detalles Bibliográficos
Autor principal: Radisky, Evette S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2020
Materias:
Scientific Commentaries
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949602/
https://www.ncbi.nlm.nih.gov/pubmed/31949898
http://dx.doi.org/10.1107/S2052252519016968
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author Radisky, Evette S.
author_facet Radisky, Evette S.
author_sort Radisky, Evette S.
collection PubMed
description Guevara, Rodriguez-Banqueri et al. [(2020), IUCrJ, 7, 18–29] determine crystal structures of mirolysin, a metalloprotease that helps oral pathogen Tannerella forsythia evade the human immune response. The structures provide insight into the regulation and specificity of mirolysin, and hint at how it might be inhibited for therapeutic effect.
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spelling pubmed-69496022020-01-16 Mirolysin structures open a window on gum disease Radisky, Evette S. IUCrJ Scientific Commentaries Guevara, Rodriguez-Banqueri et al. [(2020), IUCrJ, 7, 18–29] determine crystal structures of mirolysin, a metalloprotease that helps oral pathogen Tannerella forsythia evade the human immune response. The structures provide insight into the regulation and specificity of mirolysin, and hint at how it might be inhibited for therapeutic effect. International Union of Crystallography 2020-01-01 /pmc/articles/PMC6949602/ /pubmed/31949898 http://dx.doi.org/10.1107/S2052252519016968 Text en © Evette S. Radisky 2020 http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution (CC-BY) Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.http://creativecommons.org/licenses/by/4.0/
spellingShingle Scientific Commentaries
Radisky, Evette S.
Mirolysin structures open a window on gum disease
title Mirolysin structures open a window on gum disease
title_full Mirolysin structures open a window on gum disease
title_fullStr Mirolysin structures open a window on gum disease
title_full_unstemmed Mirolysin structures open a window on gum disease
title_short Mirolysin structures open a window on gum disease
title_sort mirolysin structures open a window on gum disease
topic Scientific Commentaries
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949602/
https://www.ncbi.nlm.nih.gov/pubmed/31949898
http://dx.doi.org/10.1107/S2052252519016968
work_keys_str_mv AT radiskyevettes mirolysinstructuresopenawindowongumdisease

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