Cargando…

Do Probiotics Improve the Health Status of Individuals with Diabetes Mellitus? A Review on Outcomes of Clinical Trials

Probiotics are now considered as an adjuvant and complementary therapeutic agent for several health complications, especially for metabolic and gastrointestinal disorders because of the influential impact of probiotic consumption on gut microbiota and immunity. Diabetes mellitus (DM) is fourth, in n...

Descripción completa

Detalles Bibliográficos
Autores principales: Kesika, Periyanaina, Sivamaruthi, Bhagavathi Sundaram, Chaiyasut, Chaiyavat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949658/
https://www.ncbi.nlm.nih.gov/pubmed/31950031
http://dx.doi.org/10.1155/2019/1531567
_version_ 1783485931123113984
author Kesika, Periyanaina
Sivamaruthi, Bhagavathi Sundaram
Chaiyasut, Chaiyavat
author_facet Kesika, Periyanaina
Sivamaruthi, Bhagavathi Sundaram
Chaiyasut, Chaiyavat
author_sort Kesika, Periyanaina
collection PubMed
description Probiotics are now considered as an adjuvant and complementary therapeutic agent for several health complications, especially for metabolic and gastrointestinal disorders because of the influential impact of probiotic consumption on gut microbiota and immunity. Diabetes mellitus (DM) is fourth, in noncommunicable disease category, leading cause of mortality, morbidity, and economic crises in the world. Though several progressions are added in the medical field in recent decades, the treatment and management of diabetic-related health issues are still challenging. The present study summarizes the effects of probiotic supplementation on the health status of diabetic patients. The relevant information was collected from Scopus, PubMed, and Google Scholar. The detailed literature survey revealed that the consumption of probiotic supplementation significantly improved the overall health condition of diabetic patients. Especially, the probiotic intervention improved the fasting blood glucose, insulin sensitivity, and systemic inflammatory and antioxidant status in type 2 diabetic (T2D) patients. Moreover, improvement of gut microbial composition and prevention of bacterial translocation has also been observed in probiotic-supplemented T2D people. Some of the studies evidenced that the supplementation of probiotics can prevent and improve the gestational DM. Nevertheless, some of the studies reported negative results and limitations in the results of clinical trials. However, further studies are mandatory to develop a concrete probiotic-based adjuvant treatment procedure to treat DM.
format Online
Article
Text
id pubmed-6949658
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Hindawi
record_format MEDLINE/PubMed
spelling pubmed-69496582020-01-16 Do Probiotics Improve the Health Status of Individuals with Diabetes Mellitus? A Review on Outcomes of Clinical Trials Kesika, Periyanaina Sivamaruthi, Bhagavathi Sundaram Chaiyasut, Chaiyavat Biomed Res Int Review Article Probiotics are now considered as an adjuvant and complementary therapeutic agent for several health complications, especially for metabolic and gastrointestinal disorders because of the influential impact of probiotic consumption on gut microbiota and immunity. Diabetes mellitus (DM) is fourth, in noncommunicable disease category, leading cause of mortality, morbidity, and economic crises in the world. Though several progressions are added in the medical field in recent decades, the treatment and management of diabetic-related health issues are still challenging. The present study summarizes the effects of probiotic supplementation on the health status of diabetic patients. The relevant information was collected from Scopus, PubMed, and Google Scholar. The detailed literature survey revealed that the consumption of probiotic supplementation significantly improved the overall health condition of diabetic patients. Especially, the probiotic intervention improved the fasting blood glucose, insulin sensitivity, and systemic inflammatory and antioxidant status in type 2 diabetic (T2D) patients. Moreover, improvement of gut microbial composition and prevention of bacterial translocation has also been observed in probiotic-supplemented T2D people. Some of the studies evidenced that the supplementation of probiotics can prevent and improve the gestational DM. Nevertheless, some of the studies reported negative results and limitations in the results of clinical trials. However, further studies are mandatory to develop a concrete probiotic-based adjuvant treatment procedure to treat DM. Hindawi 2019-12-14 /pmc/articles/PMC6949658/ /pubmed/31950031 http://dx.doi.org/10.1155/2019/1531567 Text en Copyright © 2019 Periyanaina Kesika et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Kesika, Periyanaina
Sivamaruthi, Bhagavathi Sundaram
Chaiyasut, Chaiyavat
Do Probiotics Improve the Health Status of Individuals with Diabetes Mellitus? A Review on Outcomes of Clinical Trials
title Do Probiotics Improve the Health Status of Individuals with Diabetes Mellitus? A Review on Outcomes of Clinical Trials
title_full Do Probiotics Improve the Health Status of Individuals with Diabetes Mellitus? A Review on Outcomes of Clinical Trials
title_fullStr Do Probiotics Improve the Health Status of Individuals with Diabetes Mellitus? A Review on Outcomes of Clinical Trials
title_full_unstemmed Do Probiotics Improve the Health Status of Individuals with Diabetes Mellitus? A Review on Outcomes of Clinical Trials
title_short Do Probiotics Improve the Health Status of Individuals with Diabetes Mellitus? A Review on Outcomes of Clinical Trials
title_sort do probiotics improve the health status of individuals with diabetes mellitus? a review on outcomes of clinical trials
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949658/
https://www.ncbi.nlm.nih.gov/pubmed/31950031
http://dx.doi.org/10.1155/2019/1531567
work_keys_str_mv AT kesikaperiyanaina doprobioticsimprovethehealthstatusofindividualswithdiabetesmellitusareviewonoutcomesofclinicaltrials
AT sivamaruthibhagavathisundaram doprobioticsimprovethehealthstatusofindividualswithdiabetesmellitusareviewonoutcomesofclinicaltrials
AT chaiyasutchaiyavat doprobioticsimprovethehealthstatusofindividualswithdiabetesmellitusareviewonoutcomesofclinicaltrials