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Study of the Binding Interaction between Wortmannin and Calf Thymus DNA: Multispectroscopic and Molecular Docking Studies

INTRODUCTION: Wortmannin (WTN) is a steroid metabolite that inhibits phosphatidylinositol 3-kinase and other signaling pathways. Structurally, the WTN consists of a cyclopentanophenanthrene-like structure with several oxygen-rich moieties which have the potential to interact with deoxyribonucleic ac...

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Detalles Bibliográficos
Autores principales:	Mehran, Shiva, Rasmi, Yousef, Karamdel, Hamid Reza, Hossinzadeh, Ramin, Gholinejad, Zafar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949734/ https://www.ncbi.nlm.nih.gov/pubmed/31975999 http://dx.doi.org/10.1155/2019/4936351

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