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Probing the Interactions of Sulfur-Containing Histidine Compounds with Human Gamma-Glutamyl Transpeptidase

Gamma-glutamyl transpeptidase (GGT) is a cell surface enzyme involved in glutathione metabolism and maintenance of redox homeostasis. High expression of GGT on tumor cells is associated with an increase of cell proliferation and resistance against chemotherapy. GGT inhibitors that have been evaluate...

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Detalles Bibliográficos
Autores principales: Milito, Alfonsina, Brancaccio, Mariarita, Lisurek, Michael, Masullo, Mariorosario, Palumbo, Anna, Castellano, Immacolata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949936/
https://www.ncbi.nlm.nih.gov/pubmed/31757046
http://dx.doi.org/10.3390/md17120650

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