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Probing the Interactions of Sulfur-Containing Histidine Compounds with Human Gamma-Glutamyl Transpeptidase
Gamma-glutamyl transpeptidase (GGT) is a cell surface enzyme involved in glutathione metabolism and maintenance of redox homeostasis. High expression of GGT on tumor cells is associated with an increase of cell proliferation and resistance against chemotherapy. GGT inhibitors that have been evaluate...
Autores principales: | Milito, Alfonsina, Brancaccio, Mariarita, Lisurek, Michael, Masullo, Mariorosario, Palumbo, Anna, Castellano, Immacolata |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949936/ https://www.ncbi.nlm.nih.gov/pubmed/31757046 http://dx.doi.org/10.3390/md17120650 |
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