Bioactive Nitrogenous Secondary Metabolites from the Marine Sponge Genus Haliclona

Marine sponge genus Haliclona, one of the most prolific sources of natural products, contains over 600 species but only a small part of them had been classified and chemically investigated. On the basis of extensive literature search, this review firstly summarizes 112 nitrogenous secondary metaboli...

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Detalles Bibliográficos
Autores principales: Zhu, Jiaying, Liu, Yang, Liu, Zijun, Wang, Hao, Zhang, Huawei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949942/
https://www.ncbi.nlm.nih.gov/pubmed/31816961
http://dx.doi.org/10.3390/md17120682
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author Zhu, Jiaying
Liu, Yang
Liu, Zijun
Wang, Hao
Zhang, Huawei
author_facet Zhu, Jiaying
Liu, Yang
Liu, Zijun
Wang, Hao
Zhang, Huawei
author_sort Zhu, Jiaying
collection PubMed
description Marine sponge genus Haliclona, one of the most prolific sources of natural products, contains over 600 species but only a small part of them had been classified and chemically investigated. On the basis of extensive literature search, this review firstly summarizes 112 nitrogenous secondary metabolites from classified and unclassified Haliclona sponges as well as from their symbiotic microorganisms. Most of these substances have only been found in Haliclona sponges, and display diverse bioactive properties with potential applications in new drug discovery.
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spelling pubmed-69499422020-01-16 Bioactive Nitrogenous Secondary Metabolites from the Marine Sponge Genus Haliclona Zhu, Jiaying Liu, Yang Liu, Zijun Wang, Hao Zhang, Huawei Mar Drugs Review Marine sponge genus Haliclona, one of the most prolific sources of natural products, contains over 600 species but only a small part of them had been classified and chemically investigated. On the basis of extensive literature search, this review firstly summarizes 112 nitrogenous secondary metabolites from classified and unclassified Haliclona sponges as well as from their symbiotic microorganisms. Most of these substances have only been found in Haliclona sponges, and display diverse bioactive properties with potential applications in new drug discovery. MDPI 2019-12-03 /pmc/articles/PMC6949942/ /pubmed/31816961 http://dx.doi.org/10.3390/md17120682 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Zhu, Jiaying
Liu, Yang
Liu, Zijun
Wang, Hao
Zhang, Huawei
Bioactive Nitrogenous Secondary Metabolites from the Marine Sponge Genus Haliclona
title Bioactive Nitrogenous Secondary Metabolites from the Marine Sponge Genus Haliclona
title_full Bioactive Nitrogenous Secondary Metabolites from the Marine Sponge Genus Haliclona
title_fullStr Bioactive Nitrogenous Secondary Metabolites from the Marine Sponge Genus Haliclona
title_full_unstemmed Bioactive Nitrogenous Secondary Metabolites from the Marine Sponge Genus Haliclona
title_short Bioactive Nitrogenous Secondary Metabolites from the Marine Sponge Genus Haliclona
title_sort bioactive nitrogenous secondary metabolites from the marine sponge genus haliclona
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949942/
https://www.ncbi.nlm.nih.gov/pubmed/31816961
http://dx.doi.org/10.3390/md17120682
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