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Untargeted Metabolomics-Based Screening Method for Inborn Errors of Metabolism using Semi-Automatic Sample Preparation with an UHPLC- Orbitrap-MS Platform

Routine diagnostic screening of inborn errors of metabolism (IEM) is currently performed by different targeted analyses of known biomarkers. This approach is time-consuming, targets a limited number of biomarkers and will not identify new biomarkers. Untargeted metabolomics generates a global metabo...

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Detalles Bibliográficos
Autores principales:	Bonte, Ramon, Bongaerts, Michiel, Demirdas, Serwet, Langendonk, Janneke G., Huidekoper, Hidde H., Williams, Monique, Onkenhout, Willem, Jacobs, Edwin H., Blom, Henk J., Ruijter, George J. G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6950026/ https://www.ncbi.nlm.nih.gov/pubmed/31779119 http://dx.doi.org/10.3390/metabo9120289

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