Repeated Oral Administration of a KDEL-Tagged Recombinant Cholera Toxin B Subunit Effectively Mitigates DSS Colitis despite a Robust Immunogenic Response

Cholera toxin B subunit (CTB), a non-toxic homopentameric component of Vibrio cholerae holotoxin, is an oral cholera vaccine antigen that induces an anti-toxin antibody response. Recently, we demonstrated that a recombinant CTB variant with a Lys-Asp-Glu-Leu (KDEL) endoplasmic reticulum retention mo...

Descripción completa

Detalles Bibliográficos
Autores principales: Royal, Joshua M., Reeves, Micaela A., Matoba, Nobuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6950078/
https://www.ncbi.nlm.nih.gov/pubmed/31756977
http://dx.doi.org/10.3390/toxins11120678

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6950078/
https://www.ncbi.nlm.nih.gov/pubmed/31756977
http://dx.doi.org/10.3390/toxins11120678

Ejemplares similares