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Evaluation of cognitive rehabilitation on the cognitive performance in multiple sclerosis: A randomized controlled trial

BACKGROUND: Multiple sclerosis (MS) can involve cognitive entities, including memory, attention, performance, and information processing. Furthermore, MS causes depression and negatively affects the quality of life (QOL). This study was aimed to assess the efficacy of cognitive rehabilitation on cog...

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Autores principales: Shahpouri, Mohammad Mahdi, Barekatain, Majid, Tavakoli, Mahgol, Sanaei, Shahin, Shaygannejad, Vahid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6950338/
https://www.ncbi.nlm.nih.gov/pubmed/31949461
http://dx.doi.org/10.4103/jrms.JRMS_124_19
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author Shahpouri, Mohammad Mahdi
Barekatain, Majid
Tavakoli, Mahgol
Sanaei, Shahin
Shaygannejad, Vahid
author_facet Shahpouri, Mohammad Mahdi
Barekatain, Majid
Tavakoli, Mahgol
Sanaei, Shahin
Shaygannejad, Vahid
author_sort Shahpouri, Mohammad Mahdi
collection PubMed
description BACKGROUND: Multiple sclerosis (MS) can involve cognitive entities, including memory, attention, performance, and information processing. Furthermore, MS causes depression and negatively affects the quality of life (QOL). This study was aimed to assess the efficacy of cognitive rehabilitation on cognitive entities of MS patients. MATERIALS AND METHODS: This is a clinical trial study conducted on 56 MS patients in 2016–2017. Patients were randomly divided into two Groups of A (cognitive rehabilitation) and B (control group). Patients were evaluated in terms of memory, attention, QOL, and depression. Questionnaires included Abbreviated Mental Test, Prospective and Retrospective Memory Questionnaire, Everyday Memory Questionnaire, Digit Spam test for attention assessment, QOL-54 questionnaire, and Second version of Beck questionnaire assessing depression. They were filled through an interview before the study initiation, and then, the intervention group underwent ten sessions of cognitive rehabilitation and questionnaires refilled within 3 months after study initiation. Outcomes of the two groups were compared. RESULTS: Memory, attention, QOL, and depression improved significantly following the intervention in cases (P < 0.05), while no significant change was observed among controls (P > 0.05). Comparison of cases and controls in the second evaluation showed a significant difference between cases and controls (P < 0.05). CONCLUSION: Ten sessions of cognitive rehabilitation could significantly improve MS patients' cognitive performance. Moreover, this approach affected their QOL and sense of depression in a decisive trend. It can be concluded that cognitive rehabilitation can successfully affect numerous aspects of MS patients, while numerous medical therapies may be required for treatment of each mere aspect. Further evaluations are strongly recommended.
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spelling pubmed-69503382020-01-16 Evaluation of cognitive rehabilitation on the cognitive performance in multiple sclerosis: A randomized controlled trial Shahpouri, Mohammad Mahdi Barekatain, Majid Tavakoli, Mahgol Sanaei, Shahin Shaygannejad, Vahid J Res Med Sci Original Article BACKGROUND: Multiple sclerosis (MS) can involve cognitive entities, including memory, attention, performance, and information processing. Furthermore, MS causes depression and negatively affects the quality of life (QOL). This study was aimed to assess the efficacy of cognitive rehabilitation on cognitive entities of MS patients. MATERIALS AND METHODS: This is a clinical trial study conducted on 56 MS patients in 2016–2017. Patients were randomly divided into two Groups of A (cognitive rehabilitation) and B (control group). Patients were evaluated in terms of memory, attention, QOL, and depression. Questionnaires included Abbreviated Mental Test, Prospective and Retrospective Memory Questionnaire, Everyday Memory Questionnaire, Digit Spam test for attention assessment, QOL-54 questionnaire, and Second version of Beck questionnaire assessing depression. They were filled through an interview before the study initiation, and then, the intervention group underwent ten sessions of cognitive rehabilitation and questionnaires refilled within 3 months after study initiation. Outcomes of the two groups were compared. RESULTS: Memory, attention, QOL, and depression improved significantly following the intervention in cases (P < 0.05), while no significant change was observed among controls (P > 0.05). Comparison of cases and controls in the second evaluation showed a significant difference between cases and controls (P < 0.05). CONCLUSION: Ten sessions of cognitive rehabilitation could significantly improve MS patients' cognitive performance. Moreover, this approach affected their QOL and sense of depression in a decisive trend. It can be concluded that cognitive rehabilitation can successfully affect numerous aspects of MS patients, while numerous medical therapies may be required for treatment of each mere aspect. Further evaluations are strongly recommended. Wolters Kluwer - Medknow 2019-12-23 /pmc/articles/PMC6950338/ /pubmed/31949461 http://dx.doi.org/10.4103/jrms.JRMS_124_19 Text en Copyright: © 2019 Journal of Research in Medical Sciences http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Shahpouri, Mohammad Mahdi
Barekatain, Majid
Tavakoli, Mahgol
Sanaei, Shahin
Shaygannejad, Vahid
Evaluation of cognitive rehabilitation on the cognitive performance in multiple sclerosis: A randomized controlled trial
title Evaluation of cognitive rehabilitation on the cognitive performance in multiple sclerosis: A randomized controlled trial
title_full Evaluation of cognitive rehabilitation on the cognitive performance in multiple sclerosis: A randomized controlled trial
title_fullStr Evaluation of cognitive rehabilitation on the cognitive performance in multiple sclerosis: A randomized controlled trial
title_full_unstemmed Evaluation of cognitive rehabilitation on the cognitive performance in multiple sclerosis: A randomized controlled trial
title_short Evaluation of cognitive rehabilitation on the cognitive performance in multiple sclerosis: A randomized controlled trial
title_sort evaluation of cognitive rehabilitation on the cognitive performance in multiple sclerosis: a randomized controlled trial
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6950338/
https://www.ncbi.nlm.nih.gov/pubmed/31949461
http://dx.doi.org/10.4103/jrms.JRMS_124_19
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