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First Description of Histopathological Lesions associated with a Fatal Infection of Moose (Alces Alces) with the Liver Fluke Parafasciolopsis Fasciolaemorpha Ejsmont, 1932

INTRODUCTION: Parafasciolopsis fasciolaemorpha is a liver fluke typically parasitising moose in Central and Eastern Europe. The aim of our studies was to describe a case of fatal moose parafasciolopsosis, with special emphasis on the histopathological changes caused in the liver tissue by around 10,...

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Autores principales: Filip-Hutsch, Katarzyna, Hutsch, Tomasz, Kolasa, Szymon, Demiaszkiewicz, Aleksander W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sciendo 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6950432/
https://www.ncbi.nlm.nih.gov/pubmed/31934666
http://dx.doi.org/10.2478/jvetres-2019-0068
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author Filip-Hutsch, Katarzyna
Hutsch, Tomasz
Kolasa, Szymon
Demiaszkiewicz, Aleksander W.
author_facet Filip-Hutsch, Katarzyna
Hutsch, Tomasz
Kolasa, Szymon
Demiaszkiewicz, Aleksander W.
author_sort Filip-Hutsch, Katarzyna
collection PubMed
description INTRODUCTION: Parafasciolopsis fasciolaemorpha is a liver fluke typically parasitising moose in Central and Eastern Europe. The aim of our studies was to describe a case of fatal moose parafasciolopsosis, with special emphasis on the histopathological changes caused in the liver tissue by around 10,000 flukes. MATERIAL AND METHODS: A male moose, found dead in Polesie National Park, eastern Poland, was subjected to parasitological necropsy. Macroscopic and histopathological examination of the liver was performed. RESULTS: Over 10,000 flukes identified as P. fasciolaemorpha were isolated from the liver parenchyma. Histopathological examination of the liver revealed the presence of multiple cavities, which were filled with flukes and cellular detritus and encysted with a layered capsule of connective tissue. Extensive liver fibrosis with signs of incomplete septal cirrhosis was also observed. CONCLUSION: Parafasciolopsosis with accompanying diarrhoea was the most probable reason for the moose’s death. However, it is possible that most moose are able to survive extremely intensive P. fasciolaemorpha infection by formation of extensive fibrosis, which isolates flukes from the liver parenchyma and therefore retards the failure of the organ. To the best of our knowledge, this is the first histopathological description of changes in the liver of a moose infected with P. fasciolaemorpha.
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spelling pubmed-69504322020-01-13 First Description of Histopathological Lesions associated with a Fatal Infection of Moose (Alces Alces) with the Liver Fluke Parafasciolopsis Fasciolaemorpha Ejsmont, 1932 Filip-Hutsch, Katarzyna Hutsch, Tomasz Kolasa, Szymon Demiaszkiewicz, Aleksander W. J Vet Res Original Article INTRODUCTION: Parafasciolopsis fasciolaemorpha is a liver fluke typically parasitising moose in Central and Eastern Europe. The aim of our studies was to describe a case of fatal moose parafasciolopsosis, with special emphasis on the histopathological changes caused in the liver tissue by around 10,000 flukes. MATERIAL AND METHODS: A male moose, found dead in Polesie National Park, eastern Poland, was subjected to parasitological necropsy. Macroscopic and histopathological examination of the liver was performed. RESULTS: Over 10,000 flukes identified as P. fasciolaemorpha were isolated from the liver parenchyma. Histopathological examination of the liver revealed the presence of multiple cavities, which were filled with flukes and cellular detritus and encysted with a layered capsule of connective tissue. Extensive liver fibrosis with signs of incomplete septal cirrhosis was also observed. CONCLUSION: Parafasciolopsosis with accompanying diarrhoea was the most probable reason for the moose’s death. However, it is possible that most moose are able to survive extremely intensive P. fasciolaemorpha infection by formation of extensive fibrosis, which isolates flukes from the liver parenchyma and therefore retards the failure of the organ. To the best of our knowledge, this is the first histopathological description of changes in the liver of a moose infected with P. fasciolaemorpha. Sciendo 2019-11-16 /pmc/articles/PMC6950432/ /pubmed/31934666 http://dx.doi.org/10.2478/jvetres-2019-0068 Text en © 2019 K. Filip-Hutsch et al. published by Sciendo http://creativecommons.org/licenses/by-nc-nd/3.0 This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.
spellingShingle Original Article
Filip-Hutsch, Katarzyna
Hutsch, Tomasz
Kolasa, Szymon
Demiaszkiewicz, Aleksander W.
First Description of Histopathological Lesions associated with a Fatal Infection of Moose (Alces Alces) with the Liver Fluke Parafasciolopsis Fasciolaemorpha Ejsmont, 1932
title First Description of Histopathological Lesions associated with a Fatal Infection of Moose (Alces Alces) with the Liver Fluke Parafasciolopsis Fasciolaemorpha Ejsmont, 1932
title_full First Description of Histopathological Lesions associated with a Fatal Infection of Moose (Alces Alces) with the Liver Fluke Parafasciolopsis Fasciolaemorpha Ejsmont, 1932
title_fullStr First Description of Histopathological Lesions associated with a Fatal Infection of Moose (Alces Alces) with the Liver Fluke Parafasciolopsis Fasciolaemorpha Ejsmont, 1932
title_full_unstemmed First Description of Histopathological Lesions associated with a Fatal Infection of Moose (Alces Alces) with the Liver Fluke Parafasciolopsis Fasciolaemorpha Ejsmont, 1932
title_short First Description of Histopathological Lesions associated with a Fatal Infection of Moose (Alces Alces) with the Liver Fluke Parafasciolopsis Fasciolaemorpha Ejsmont, 1932
title_sort first description of histopathological lesions associated with a fatal infection of moose (alces alces) with the liver fluke parafasciolopsis fasciolaemorpha ejsmont, 1932
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6950432/
https://www.ncbi.nlm.nih.gov/pubmed/31934666
http://dx.doi.org/10.2478/jvetres-2019-0068
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