Cargando…

Role of Jumpstart Nutrition(®), a Dietary Supplement, to Ameliorate Calcium-to-Phosphorus Ratio and Parathyroid Hormone of Patients with Osteoarthritis

The aim of this study was to use Jumpstart Nutrition(®) bone supplementing combination with vitamin-K(2) and coenzyme-Q(10) characterized by an innovative delivery system that improves bioavailability of calcium-to-phosphorus ratio (CPR) and parathyroid hormone (PTH) in the management of osteoarthri...

Descripción completa

Detalles Bibliográficos
Autor principal: Ganguly, Apurba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6950452/
https://www.ncbi.nlm.nih.gov/pubmed/31766751
http://dx.doi.org/10.3390/medsci7120105
_version_ 1783486075262468096
author Ganguly, Apurba
author_facet Ganguly, Apurba
author_sort Ganguly, Apurba
collection PubMed
description The aim of this study was to use Jumpstart Nutrition(®) bone supplementing combination with vitamin-K(2) and coenzyme-Q(10) characterized by an innovative delivery system that improves bioavailability of calcium-to-phosphorus ratio (CPR) and parathyroid hormone (PTH) in the management of osteoarthritis (OA). This eight-week registry included 108 patients treated for symptomatic OA confirmed with radiological images. On top of that, 63 patients used Jumpstart Nutrition(®) supplement, mainly prepared with calcium, phosphorus, coenzyme-Q(10), vitamin-K(2), vitamin-D(2), vitamin-C, folic acid, curcumin and boswellic acids. Rescue medication was also recommended. Patients’ pain and functional capacity through outcome measures—knee-injury osteoarthritis outcome scale (KOOS) and Karnofsky performance scale (KPS), biomarkers such as levels of CPR, PTH and 25-hydroxy-vitamin-D were evaluated for the groups with and without supplement using appropriate kits. After eight weeks, the levels of CPR and PTH were all significantly improved (p < 0.001), fewer subjects had to use rescue medication (p < 0.05) and variation of pain and functional capacity under KOOS and KPS (p < 0.05) of the patients in the supplement group compared to controls. This registry study indicates that Jumpstart Nutrition(®) can be used safely for effective management of OA patients for the amelioration of CPR, PTH and functional activities confirmed with biomarkers and radiological images correlated with the Kellgren-Lawrance scale.
format Online
Article
Text
id pubmed-6950452
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-69504522020-01-16 Role of Jumpstart Nutrition(®), a Dietary Supplement, to Ameliorate Calcium-to-Phosphorus Ratio and Parathyroid Hormone of Patients with Osteoarthritis Ganguly, Apurba Med Sci (Basel) Article The aim of this study was to use Jumpstart Nutrition(®) bone supplementing combination with vitamin-K(2) and coenzyme-Q(10) characterized by an innovative delivery system that improves bioavailability of calcium-to-phosphorus ratio (CPR) and parathyroid hormone (PTH) in the management of osteoarthritis (OA). This eight-week registry included 108 patients treated for symptomatic OA confirmed with radiological images. On top of that, 63 patients used Jumpstart Nutrition(®) supplement, mainly prepared with calcium, phosphorus, coenzyme-Q(10), vitamin-K(2), vitamin-D(2), vitamin-C, folic acid, curcumin and boswellic acids. Rescue medication was also recommended. Patients’ pain and functional capacity through outcome measures—knee-injury osteoarthritis outcome scale (KOOS) and Karnofsky performance scale (KPS), biomarkers such as levels of CPR, PTH and 25-hydroxy-vitamin-D were evaluated for the groups with and without supplement using appropriate kits. After eight weeks, the levels of CPR and PTH were all significantly improved (p < 0.001), fewer subjects had to use rescue medication (p < 0.05) and variation of pain and functional capacity under KOOS and KPS (p < 0.05) of the patients in the supplement group compared to controls. This registry study indicates that Jumpstart Nutrition(®) can be used safely for effective management of OA patients for the amelioration of CPR, PTH and functional activities confirmed with biomarkers and radiological images correlated with the Kellgren-Lawrance scale. MDPI 2019-11-22 /pmc/articles/PMC6950452/ /pubmed/31766751 http://dx.doi.org/10.3390/medsci7120105 Text en © 2019 by the author. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Ganguly, Apurba
Role of Jumpstart Nutrition(®), a Dietary Supplement, to Ameliorate Calcium-to-Phosphorus Ratio and Parathyroid Hormone of Patients with Osteoarthritis
title Role of Jumpstart Nutrition(®), a Dietary Supplement, to Ameliorate Calcium-to-Phosphorus Ratio and Parathyroid Hormone of Patients with Osteoarthritis
title_full Role of Jumpstart Nutrition(®), a Dietary Supplement, to Ameliorate Calcium-to-Phosphorus Ratio and Parathyroid Hormone of Patients with Osteoarthritis
title_fullStr Role of Jumpstart Nutrition(®), a Dietary Supplement, to Ameliorate Calcium-to-Phosphorus Ratio and Parathyroid Hormone of Patients with Osteoarthritis
title_full_unstemmed Role of Jumpstart Nutrition(®), a Dietary Supplement, to Ameliorate Calcium-to-Phosphorus Ratio and Parathyroid Hormone of Patients with Osteoarthritis
title_short Role of Jumpstart Nutrition(®), a Dietary Supplement, to Ameliorate Calcium-to-Phosphorus Ratio and Parathyroid Hormone of Patients with Osteoarthritis
title_sort role of jumpstart nutrition(®), a dietary supplement, to ameliorate calcium-to-phosphorus ratio and parathyroid hormone of patients with osteoarthritis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6950452/
https://www.ncbi.nlm.nih.gov/pubmed/31766751
http://dx.doi.org/10.3390/medsci7120105
work_keys_str_mv AT gangulyapurba roleofjumpstartnutritionadietarysupplementtoamelioratecalciumtophosphorusratioandparathyroidhormoneofpatientswithosteoarthritis