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Role of Jumpstart Nutrition(®), a Dietary Supplement, to Ameliorate Calcium-to-Phosphorus Ratio and Parathyroid Hormone of Patients with Osteoarthritis
The aim of this study was to use Jumpstart Nutrition(®) bone supplementing combination with vitamin-K(2) and coenzyme-Q(10) characterized by an innovative delivery system that improves bioavailability of calcium-to-phosphorus ratio (CPR) and parathyroid hormone (PTH) in the management of osteoarthri...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6950452/ https://www.ncbi.nlm.nih.gov/pubmed/31766751 http://dx.doi.org/10.3390/medsci7120105 |
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author | Ganguly, Apurba |
author_facet | Ganguly, Apurba |
author_sort | Ganguly, Apurba |
collection | PubMed |
description | The aim of this study was to use Jumpstart Nutrition(®) bone supplementing combination with vitamin-K(2) and coenzyme-Q(10) characterized by an innovative delivery system that improves bioavailability of calcium-to-phosphorus ratio (CPR) and parathyroid hormone (PTH) in the management of osteoarthritis (OA). This eight-week registry included 108 patients treated for symptomatic OA confirmed with radiological images. On top of that, 63 patients used Jumpstart Nutrition(®) supplement, mainly prepared with calcium, phosphorus, coenzyme-Q(10), vitamin-K(2), vitamin-D(2), vitamin-C, folic acid, curcumin and boswellic acids. Rescue medication was also recommended. Patients’ pain and functional capacity through outcome measures—knee-injury osteoarthritis outcome scale (KOOS) and Karnofsky performance scale (KPS), biomarkers such as levels of CPR, PTH and 25-hydroxy-vitamin-D were evaluated for the groups with and without supplement using appropriate kits. After eight weeks, the levels of CPR and PTH were all significantly improved (p < 0.001), fewer subjects had to use rescue medication (p < 0.05) and variation of pain and functional capacity under KOOS and KPS (p < 0.05) of the patients in the supplement group compared to controls. This registry study indicates that Jumpstart Nutrition(®) can be used safely for effective management of OA patients for the amelioration of CPR, PTH and functional activities confirmed with biomarkers and radiological images correlated with the Kellgren-Lawrance scale. |
format | Online Article Text |
id | pubmed-6950452 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-69504522020-01-16 Role of Jumpstart Nutrition(®), a Dietary Supplement, to Ameliorate Calcium-to-Phosphorus Ratio and Parathyroid Hormone of Patients with Osteoarthritis Ganguly, Apurba Med Sci (Basel) Article The aim of this study was to use Jumpstart Nutrition(®) bone supplementing combination with vitamin-K(2) and coenzyme-Q(10) characterized by an innovative delivery system that improves bioavailability of calcium-to-phosphorus ratio (CPR) and parathyroid hormone (PTH) in the management of osteoarthritis (OA). This eight-week registry included 108 patients treated for symptomatic OA confirmed with radiological images. On top of that, 63 patients used Jumpstart Nutrition(®) supplement, mainly prepared with calcium, phosphorus, coenzyme-Q(10), vitamin-K(2), vitamin-D(2), vitamin-C, folic acid, curcumin and boswellic acids. Rescue medication was also recommended. Patients’ pain and functional capacity through outcome measures—knee-injury osteoarthritis outcome scale (KOOS) and Karnofsky performance scale (KPS), biomarkers such as levels of CPR, PTH and 25-hydroxy-vitamin-D were evaluated for the groups with and without supplement using appropriate kits. After eight weeks, the levels of CPR and PTH were all significantly improved (p < 0.001), fewer subjects had to use rescue medication (p < 0.05) and variation of pain and functional capacity under KOOS and KPS (p < 0.05) of the patients in the supplement group compared to controls. This registry study indicates that Jumpstart Nutrition(®) can be used safely for effective management of OA patients for the amelioration of CPR, PTH and functional activities confirmed with biomarkers and radiological images correlated with the Kellgren-Lawrance scale. MDPI 2019-11-22 /pmc/articles/PMC6950452/ /pubmed/31766751 http://dx.doi.org/10.3390/medsci7120105 Text en © 2019 by the author. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Ganguly, Apurba Role of Jumpstart Nutrition(®), a Dietary Supplement, to Ameliorate Calcium-to-Phosphorus Ratio and Parathyroid Hormone of Patients with Osteoarthritis |
title | Role of Jumpstart Nutrition(®), a Dietary Supplement, to Ameliorate Calcium-to-Phosphorus Ratio and Parathyroid Hormone of Patients with Osteoarthritis |
title_full | Role of Jumpstart Nutrition(®), a Dietary Supplement, to Ameliorate Calcium-to-Phosphorus Ratio and Parathyroid Hormone of Patients with Osteoarthritis |
title_fullStr | Role of Jumpstart Nutrition(®), a Dietary Supplement, to Ameliorate Calcium-to-Phosphorus Ratio and Parathyroid Hormone of Patients with Osteoarthritis |
title_full_unstemmed | Role of Jumpstart Nutrition(®), a Dietary Supplement, to Ameliorate Calcium-to-Phosphorus Ratio and Parathyroid Hormone of Patients with Osteoarthritis |
title_short | Role of Jumpstart Nutrition(®), a Dietary Supplement, to Ameliorate Calcium-to-Phosphorus Ratio and Parathyroid Hormone of Patients with Osteoarthritis |
title_sort | role of jumpstart nutrition(®), a dietary supplement, to ameliorate calcium-to-phosphorus ratio and parathyroid hormone of patients with osteoarthritis |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6950452/ https://www.ncbi.nlm.nih.gov/pubmed/31766751 http://dx.doi.org/10.3390/medsci7120105 |
work_keys_str_mv | AT gangulyapurba roleofjumpstartnutritionadietarysupplementtoamelioratecalciumtophosphorusratioandparathyroidhormoneofpatientswithosteoarthritis |