Cargando…
FGF21, not GCN2, influences bone morphology due to dietary protein restrictions
BACKGROUND: Dietary protein restriction is emerging as an alternative approach to treat obesity and glucose intolerance because it markedly increases plasma fibroblast growth factor 21 (FGF21) concentrations. Similarly, dietary restriction of methionine is known to mimic metabolic effects of energy...
Autores principales: | McNulty, Margaret A., Goupil, Brad A., Albarado, Diana C., Castaño-Martinez, Teresa, Ambrosi, Thomas H., Puh, Spela, Schulz, Tim J., Schürmann, Annette, Morrison, Christopher D., Laeger, Thomas |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6950640/ https://www.ncbi.nlm.nih.gov/pubmed/31921941 http://dx.doi.org/10.1016/j.bonr.2019.100241 |
Ejemplares similares
-
Low protein-induced increases in FGF21 drive UCP1-dependent metabolic but not thermoregulatory endpoints
por: Hill, Cristal M., et al.
Publicado: (2017) -
FGF21 improves glucose homeostasis in an obese diabetes-prone mouse model independent of body fat changes
por: Laeger, Thomas, et al.
Publicado: (2017) -
FGF21 Signals Protein Status to the Brain and Adaptively Regulates Food Choice and Metabolism
por: Hill, Cristal M., et al.
Publicado: (2019) -
FGF21 is required for protein restriction to extend lifespan and improve metabolic health in male mice
por: Hill, Cristal M., et al.
Publicado: (2022) -
Dietary carbohydrates impair the protective effect of protein restriction against diabetes in NZO mice used as a model of type 2 diabetes
por: Laeger, Thomas, et al.
Publicado: (2018)