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Tumor necrosis factor α-induced protein 1 as a novel tumor suppressor through selective downregulation of CSNK2B blocks nuclear factor-κB activation in hepatocellular carcinoma

BACKGROUND: Tumor necrosis factor α-induced protein 1 (TNFAIP1) is frequently downregulated in cancer cell lines and promotes cancer cell apoptosis. However, its role, clinical significance and molecular mechanisms in hepatocellular carcinoma (HCC) are unknown. METHODS: The expression of TNFAIP1 in...

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Detalles Bibliográficos
Autores principales: Xiao, Ye, Huang, Shulan, Qiu, Feng, Ding, Xiaofeng, Sun, Yi, Wei, Chenxi, Hu, Xiang, Wei, Ke, Long, Shengwen, Xie, Lina, Xun, Yu, Chen, Wen, Zhang, Zhijian, Liu, Ning, Xiang, Shuanglin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6950786/
https://www.ncbi.nlm.nih.gov/pubmed/31901862
http://dx.doi.org/10.1016/j.ebiom.2019.102603